I have written many article in the past about the use of probiotics in Inflammatory Bowel Disease. Up to this point there was not a lot of information specific to their use in IBD but they were often prescribed in a "well, it couldn't hurt to try it" sort of way.
Less than a year ago I attended a webcast during which time I was able to ask several of the top doctors in IBD about probiotics. They seemed to think that in the future there would be specific probiotics designed to treat specific diseases. At the time it sounded like this treatment would be a long was off but recent research proves promising.
Researchers at Northwestern medicine deleted a gene in the probiotic Lactobacillus acidophilus and fed it to two groups of mice with different forms of colitis. All of the mice saw a regression of symptoms. The probiotic almost completely eliminated the inflammation in the colon and stopped the progression of the colitis by 95 percent. The researchers theorized that this ...
There was a new study published in the May 29, 2008 issue of Nature , a science and medicine journal, which may point researchers and pharmaceutical companies in a new direction of how to treat IBD . Researchers from the California Institute of Technology and Harvard Medical School teamed up to conduct a study using mice and one of the thousands of bacteria found in the mammalian gut. The researchers identified a potentially beneficial bacteria known as, Bacteroides fragilis which showed promise in restoring an immune system balance in the mice used in the study.
In the study, immune compromised mice who were identified to have a specific pathogen-free microbiotica, were administered a dose of Helicobacter hepaticus, an intestinal bacterium, and developed what the researchers called a "rip roaring" case of IBD. But, when the researchers combined B. fragilis with the Helicobacter the mice remained fine. Through further experimentation, researchers found that a particul...
What are probiotics, who should take them, and where do you
Interest in the reported health benefits of probiotics has
grown in the past decade, and researchers continue to investigate how the
supplements can treat or prevent specific illnesses. Probiotics are
well-recognized for their ability to calm bowel inflammation in certain diseases,
particularly viral diarrhea, and they're
also helpful in reducing the incidence of severe diarrhea in patients being
treated for cancer .
On the research front they are being evaluated for use
in a number of skin disorders, and a nimal
studies suggest probiotics may play a role in the prevention of cancer . But
the supplements are not universally beneficial, and they're not recommended for
all patients. Let's take a closer look at these tiny organisms and what they
What are probiotics?
Probiotics are defined as "live microbial food ingredients
that are beneficial to health." Lactobacilli and bifidobacteria are well ...
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