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I have written many article in the past about the use of probiotics in Inflammatory Bowel Disease. Up to this point there was not a lot of information specific to their use in IBD but they were often prescribed in a "well, it couldn't hurt to try it" sort of way.
Less than a year ago I attended a webcast during which time I was able to ask several of the top doctors in IBD about probiotics. They seemed to think that in the future there would be specific probiotics designed to treat specific diseases. At the time it sounded like this treatment would be a long was off but recent research proves promising.
Researchers at Northwestern medicine deleted a gene in the probiotic Lactobacillus acidophilus and fed it to two groups of mice with different forms of colitis. All of the mice saw a regression of symptoms. The probiotic almost completely eliminated the inflammation in the colon and stopped the progression of the colitis by 95 percent. The researchers theorized that this ...
Generic Name: PROBIOTICS - ORAL Probiotic & Acidophilus Oral Uses
Probiotics contain different types of micro-organisms such
as yeast (saccharomyces boulardii) and bacteria (such as lactobacillus,
bifidobacterium). Micro-organisms (flora) are naturally found in the
stomach/intestines/vagina. Some conditions (such as antibiotic use, travel) can
change the normal balance of bacteria/yeast. Probiotics are used to improve
digestion and restore normal flora.
Probiotics have been used to treat bowel problems (such as
diarrhea, irritable bowel), eczema, vaginal yeast infections, lactose
intolerance, and urinary tract infections.
Probiotics are available in foods (such as yogurt, milk,
juices, soy beverages) and as dietary supplements (capsules, tablets, powders).
Different products have different uses. Check the label for information on uses
for your particular product.
Some diet supplement products have been found to contain
There was a new study published in the May 29, 2008 issue of Nature , a science and medicine journal, which may point researchers and pharmaceutical companies in a new direction of how to treat IBD . Researchers from the California Institute of Technology and Harvard Medical School teamed up to conduct a study using mice and one of the thousands of bacteria found in the mammalian gut. The researchers identified a potentially beneficial bacteria known as, Bacteroides fragilis which showed promise in restoring an immune system balance in the mice used in the study.
In the study, immune compromised mice who were identified to have a specific pathogen-free microbiotica, were administered a dose of Helicobacter hepaticus, an intestinal bacterium, and developed what the researchers called a "rip roaring" case of IBD. But, when the researchers combined B. fragilis with the Helicobacter the mice remained fine. Through further experimentation, researchers found that a particul...
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