I was placed on Seroquel while in a inpatient psychiatric facility.  I developed severe major depression with suicidal ideations due to severe chronic pain related to work injuries and other medical conditions.  I have been placed on 600 mg Effexor, which is the maximum amount, but works for me.  I had been placed in inpatient psychiatric wards at least 6 times between 2004 and january of 2007.  The doctor at the last facility put me on large doses of Seroquel.  My psychiatrist out patient, does not want me to take more than 100mg,  However, that is not enough to put me soundly to sleep.  I take the Seroquel with one 10 mg Ambien, which puts me to sleep and the Seroquel keeps me asleep.

I have no diabetes or histor of this disease in my family and my blood work is great,  No heart conditions or any of the other issues discussed in information I found on the web.

I also take MS cotin Morphine 60 mg up to 2 per day and ocassionally Lortab 10mg for breakthrough pain.  I have up to 2 10 mg valium I can take and also take 600 mg Neurotin.  The Effexor and Seroquel, however, make it possible for me to get by with minimal amounts of the pain medications. I have not been back in an inpaitent setting since I started Seroquel.  I have been diagnosed with border line disorder and bipolar disorder, post traumatic stress disorder and major depression which started following a serious work injury.  I have also been diagnosed with numerous orthopedic problems and nerve damage and RSD.

Is 300 mg of Seroquel, which is the amount it takes to keep me asleep through the night likely to cause diabetes when there is no family history of the condition?  If so, what other medication would you recommend. I have already tried Trazadone and Thorazine and they just do not work the same as the Seroquel.