Nonsteroidal antiinflammatory drugs (NSAIDs) still remain one of the most commonly used drugs for joint pain from osteoarthritis (OA). Changes have come about over the years to improve these drugs. Reducing side effects such as stomach bleeds and kidney problems has brought a whole new generation of NSAIDs to the market. In this article, doctors from NYU Hospital for Joint Diseases in New York review current trends with NSAID use. Choosing the right NSAID for each patient is the first step. Acetaminophen (Tylenol®) is still the first choice for mild OA. Tylenol is a pain reliever but not an NSAID. When Tylenol® is not effective, an NSAID may be needed to control pain and inflammation. Aspirin used to be the most popular NSAID. But aspirin use in some people can result in ulcers, GI bleeding, and kidney failure. Scientists discovered that certain enzymes called cyclooxygenase (COX) were part of the problem. A new group of NSAIDs was developed to inhibit or stop one specific enzyme (COX-2...
Indian pharmaceutical company Panacea Biotec recently announced
that it had secured a patent for the production of its popular
non-steroidal anti-inflammatory drug (NSAID) Willgo, containing the
chemical compound nimesulide. The medication, which Panacea
introduced in 2004, relieves the chronic joint pain that is a
result of osteoarthritis, according to the company. Furthermore,
the medication is classified as Extended Release, which
means that it is designed to combat the many symptoms of
osteoarthritic joints over an extended period of time-- symptoms
that include stiffness, tenderness, swelling, as well as the
aforementioned joint pain. Panacea touts its ability to improve
functional mobility for the osteoarthritis patients who
Health care professionals depend on good sources of information to keep up-to-date on evidence-based medicine. One of the most reliable publications comes from the Cochrane Collaboration . Everyone pays attention when they publish a study. The Cochrane Collaboration is a group of over 11,500 volunteers who systematically review all relevant randomized controlled trials on a specific topic. The people in the group are located in more than 90 countries. They also study the results of non-randomized, observational studies. The results of these systematic reviews are published in the Cochrane Library. In this study, the use of nonsteroidal antiinflammatory drugs (NSAIDs) for low back pain (LBP) was reviewed. The goals were to 1) look for effects of NSAIDs and 2) find out which type of NSAID works the best. Specifically, COX-2 inhibiting NSAIDs were considered. These drugs have a lower risk of gastrointestinal side effects. For this reason, they have recently become more popular than the trad...
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