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A puzzling pain that has the same distribution of neuropathic pain, but without the typical symptoms of burning, itching, sensitive to touch, numbness or tingling. May be the pain is an atypical nerve condition or may be you are right about your bones.   Bone disease, connective tissue disease, nerve disease, and muscle disease would all be likely candidates. Finding the answer may take some additional tests like a SPECT scan (a CT/bone scan) or an MRI (which looks at soft tissues) and a nerve test (just in case of the atypical nerve pain). The swelling could also be caused by medication side effects (very typical of Lyrica).   The lumbar spine can cause many types of leg and foot pain. So, do not discount that possibility. The spine can also be the avenue for relief with a spinal cord stimulator which can block leg pain.   Sometimes, the diagnosis and exact origin of pain can remain uncertain. Try not to let that worry you too much because worrying can make the pain worse. Work with your doctor and focus on finding a solution by looking at all the angles.  Dr. Christina Lasich, MD