Generic Name: PREGABALIN - ORAL Pronounced: (pree-GAH-ba-lin) Lyrica Oral Interactions
Drug interactions may change how your medications work or
increase your risk for serious side effects. This document does not contain all
possible drug interactions. Keep a list of all the products you use (including
prescription/nonprescription drugs and herbal products) and share it with your
doctor and pharmacist. Do not start, stop, or change the dosage of any
medicines without your doctor's approval.
Tell your doctor or pharmacist if you are taking other
products that cause drowsiness including alcohol, antihistamines (such as
cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam,
diazepam, zolpidem), muscle relaxants, and narcotic pain relievers (such as
Check the labels on all your medicines (such as allergy or
cough-and-cold products) because they may contain ingredients that cause
drowsiness. Ask your ...
A case was recently reported of a 70-year-old man who developed rhabdomyolysis after his Lyrica (pregabalin) dosage was increased and he was also given Zocor (simvastatin), a statin drug usually given for high cholesterol. Rhabdomyolysis is the breakdown of muscle fibers that leads to the release of muscle fiber contents (myoglobin) into the bloodstream, which is harmful to the kidneys and often causes kidney damage.
When he arrived at the emergency room, the man was mentally disoriented, he was unable to stand up, all four extremities were twitching and he had slurred speech. Other symptoms of rhabdomyolysis may include:
Dark, red or cola colored urine
Decreased urine production
Muscle stiffness or aching
Weakness of affected muscles
Unintentional weight gain
Statin drugs are known to sometimes cause rhabdomyolysis. Lyrica is not generally recognized as a cause of rhabdomyolysis, although in t...
Two weeks ago I told you that the FDA approved a generic version of Lyrica ® (pregabalin) made by Lupin Limited, but I wasn't able to find out when it might actually be available on the market. Now I know why I couldn't find that information. Apparently Lupin was awaiting a court decision as to whether or not on Pfizer Inc.'s patents for Lyrica were valid.
That decision came down last Thursday, July 19, 2012. Judge Gregory M. Sleet of the U.S. District Court of Delaware upheld the validity of Pfizer's patents for Lyrica, giving them exclusive rights to the medication until December 30, 2018. In addition, Judge Sleet ordered the FDA to stop approving generic forms of pregabalin until Pfizer's patents expire.
The Story Behind the Decision
In 2009, Pfizer filed a lawsuit charging patent infringement against Israel's Teva Pharmaceutical Industries, India's Sun Pharmaceutical Industries, and U.S. firms Mylan and Watson Pharmaceuticals, who all sought FDA approval ...
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