There is pain in multiple sclerosis, with several categories that can be acute or chronic. My last article discussed neuropathic pain . Today, I am going to talk about details specific to musculoskeletal pain. Our musculoskeletal system -- bones, muscles, connective tissues -- provides our bodies with stability and movement. Musculoskeletal pain, also known as nociceptive pain, can seriously affect our well-being. Nociceptors are free nerve endings that detect stimuli and interpret them as pain. Nociceptors, protected by myelin, are in all types of body tissue except the brain itself. Neuropathic pain is caused by nervous system lesions while musculoskeletal pain is caused by actual tissue damage detected by the nociceptors. Musculoskeletal pain is not caused by MS, but by MS symptoms. Therefore, musculoskeletal pains are defined as secondary pain. It is often made worse by our inactivity, immobility, spasticity, and posture problems. That is, simply having multiple sclerosi...
Recent research has shown that most people who suffer from chronic musculoskeletal pain (like fibromyalgia ) are deficient in vitamin D. It further showed that when they started getting enough vitamin D, their pain improved – and in some cases vanished completely. When vitamin D is broken down by the liver and kidneys, it functions as a hormone and works throughout the body, affecting muscles, tissues, nerves, joints and even the brain. Vitamin D is also essential in order for your body to properly absorb calcium and keep your bones strong. A lack of vitamin D can cause problems leading to pain in all of these areas. Vitamin D is reported to be especially good for back pain. Other conditions it may be helpful for include:
Seasonal Affective Disorder (SAD)
How Do We Get Vitamin D? The main natural source of vitamin D is the sun. However, many factors may reduce t...
The FDA has now approved Cymbalta (duloxetine) to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain . "Up to three quarters of the population experience chronic pain at some time in their lives," said Janet Woodcock, M.D., director of FDA's Center for Drug Evaluation and Research. "This approval means that many of those people now have another treatment option." Since its initial approval in 2004, about 30 million patients in the United States have used Cymbalta. Thus far Cymbalta, manufactured by Eli Lilly and Co., has received FDA approval for six different indications, three of which are pain-related:
Major depressive disorder in 2004
Diabetic peripheral neuropathy in 2004
Generalized anxiety disorder in 2007
Maintenance treatment of major depression in 2007
Fibromyalgia in 2008
Chronic musculoskeletal pain in 2010
Cymbalta is classified as an antidepressant in a group of drugs called selective serotonin and norepi...
You should knowAnswers to your question are meant to provide general health information but should not replace medical advice you receive from a doctor. No answers should be viewed as a diagnosis or recommended treatment for a condition. Content posted by community members does not necessarily reflect the views of Remedy Health Media, which also reserves the right to remove material deemed inappropriate.