The FDA has now approved Cymbalta (duloxetine) to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain . "Up to three quarters of the population experience chronic pain at some time in their lives," said Janet Woodcock, M.D., director of FDA's Center for Drug Evaluation and Research. "This approval means that many of those people now have another treatment option." Since its initial approval in 2004, about 30 million patients in the United States have used Cymbalta. Thus far Cymbalta, manufactured by Eli Lilly and Co., has received FDA approval for six different indications, three of which are pain-related:
Major depressive disorder in 2004
Diabetic peripheral neuropathy in 2004
Generalized anxiety disorder in 2007
Maintenance treatment of major depression in 2007
Fibromyalgia in 2008
Chronic musculoskeletal pain in 2010
Cymbalta is classified as an antidepressant in a group of drugs called selective serotonin and norepi...
Last week I spoke with Melinda Beck, health columnist for the Wall Street Journal for an hour. She was interviewing me for an article she was writing about the dilemma doctors face in determining how much pain patients are really in . She had already talked with a number of pain specialists and wanted to get the patients' perspective. Her article appeared on page D1 of today's paper and can be read online here: Doctors' Challenge: How Real Is That Pain? Given the limited space she was alloted for the article, Ms. Beck did a good job of identifying the problem. Of course, I always want to see more about how the difficulties in diagnosing and treating pain affect the patients. But since her assignment was to write about how hard it is for doctors to accurately distinguish between people who are really in pain and those simply seeking drugs, I really appreciate that she took the time to ask how this problem impacts patients. So much of what we see in the ...
Definition Anterior vaginal wall repair is surgery that tightens the front ( anterior ) wall of the vagina. Alternative Names A/P repair; Vaginal wall repair; Anterior and/or posterior vaginal wall repair; Colporrhaphy - repair of vaginal wall; Cystocele repair Description This procedure may be done while you are under general or spinal anesthesia . Under general anesthesia, you will be asleep and unable to feel pain. With spinal anesthesia, you will be awake, but you will be numb from the waist down and you will not feel pain. You will be given medicines to help you relax. Usually, a surgical cut (incision) is made through the front wall of your vagina . Your bladder is moved back to its normal location. Your vaginal wall may be folded, or part of it may be cut away. Sutures (stitches) are made in the tissue between your vagina and bladder. These will hold the walls of your vagina in the correct position. Your doctor may place human-made (synthetic) material between your bladder and vagina. If needed...
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