Menopause can bring many things. One of them can be breast cancer. For instance, the American Cancer Society reports that women who experienced more menstrual cycles because they started menstruating early (before age 12) and/or went through menopause later (after age 55) face a slightly elevated risk of breast cancer, possibly due to a longer lifetime exposure to the hormones estrogen and progesterone. In addition, aging is another risk factor for breast cancer. In fact, two out of three invasive breast cancers are found in women who are 55 and older.
And the numbers of people who are stricken with breast cancer are daunting. The World Health Organization reports that there are approximately 1.3 million new cases of breast cancer annually. Furthermore, 450,000 die from this disease each year. Additionally, some places in the world are seeing increases in the number of cases diagnosed. For instance, the BBC reported in 2011 that breast cancer rates for British women who are in their 4...
Last week Lupin Pharmaceuticals, Inc. issued a press release announcing that it has received final FDA approval to market pregabalin, the generic version of Lyrica ® in the U.S.
Lyrica (pregabalin) was the first drug ever to be approved for the treatment of fibromyalgia . In addition to fibromyalgia, it has also been approved by the FDA for:
Treatment of neuropathic pain associated with diabetic peripheral neuropathy.
Treatment of post herpetic neuralgia.
Use an adjunctive therapy for adult patients with partial onset seizures.
Lupin's pregabalin capsules, to be available in 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg and 300 mg doses, are the AB-rated generic equivalent of Lyrica. An AB rating means that the generic drug has been studied and has demonstrated that it is bioequivalent to the original drug.
According to the FDA, "Bioequivalence of different formulations of the same drug substance involves equivalence with respect to the rate and ...
As of this writing, three medications have been approved by the FDA for the treatment of fibromyalgia: Lyrica (pregabalin), Cymbalta (duloxetine) and Savella (milnacipran). Since all three are relatively new drugs, information on how well they work and their side effects is still being gathered. Because every patient's symptoms and body chemistry are different, it is often a matter of trial and error to find the best medication for a particular patient with a particular illness. However, a recent German study , which was the first to compare the pros and cons of the three drugs head-to-head, may help doctors choose which medication has the best chance of success for any given patient. Study Design The study authors searched MEDLINE, SCOPUS, Cochrane Central Register of Controlled Trials, and sought unpublished data from the databases of FDA, US National Institutes for Health, and Industry through May 2009 for randomized controlled trials. They found 17...
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