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I have been on them for over 10 years straight. I have no problems at all taking them and they do the job they are made to do. But large WARNING!!!! yOUR BODY DOES BECOME ADDICTED TO THEM IN TH FIRST 6-8 WEEKS OF TAKING THEM!!!! DO NOT JUST STOP TAKING THEM COLD TURKEY IF YOU FIGURE YOU DONT NEED THE PILL BECAUSE IT DOES NOT HURT MUCH, IF YOU TAKE THEM AROUNF THE CLOCK FOR THE LAST 4 MONTHS, YOU ARE DEPENDENT ON THE OPIOD PILL. SO, YES I HAVE TAKEN ALL SORTS OFF PAIN KILLERS, AND IM ON A COMBO TODAY THAT I HAVE BEEN ON FOR OVER 3 YEARS, I HAVE HAD T MAKE VERY FEW ADJUSTMENTS TO THE MEDICATIONS DURING THAT TIME, AND I LIVE AS GOOD AS I CAN. NO DRUGGEE FEELING, NO HIGH, IT JUST TAKES CARE OF THE PAIN LIKE THEY ARE MADE TO. BUT, LIKE I SAID DONT ABUSE THEM, TELL YUR DR EVERY TIME THEY ARE NOT DOING THE JOB SO THEY KNOW THE DOSES YOU ARE TAKING, AND JUST USE THEM THE WAY YOU ARE TOLD TO AND THINGS ARE GOING TO BE OK. IT IS GOING TO TAKE SOME TIME TO KICK THE PILLS, IF YOU DO GET OFF THEM OR DO NOT NEED THEM. AND ANTHER THING, THEY ARE MUCH BETTER HEALTH WISE THEN THE ANSAIDS THEY ALL TRY TO MAKE YOU TAKE AT FIRST. THOSE ARE GOING TO KILL YOU MUCH FAST THEM THE NARC PILL ARE. THAT IS A FACT. LOOK AT ALL THE SPORTS FIGURES THAT HAVE KIDNEY FAILURE BECAUSE OF TAKING THOSE NSAIDS,(MOTRIN,NAPESON) THSE KILL YOUR STOMACH AND SHUT YOUR LIVER AND KIDNEYS OFF QUICK. SO, HOPE I HELPED AND HOPE YOU FEEL BETTER.