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Has your doctor checked you for Restless Leg Syndrome?  I suffer from RLS which is a neurological nerve problem and it is as you describe pain and cramps mostly at nighttime.  I have had cramps so bad in my calves that I wake up the next morning with bruises on my legs.  My doctor has me on klonopin once at bedtime (tried Lyrica but it causes MAJOR weigh gain).  It helps but I still have infrequent bouts with the leg cramps and pain - also with leg "twitching" or "jumping" that cannot be controlled.  Hope this helps some and good luck to you.