Is there a difference between Lortab and Trezix?
Both are strong pain relievers. Trezix has dihydrocodeine and acetaminophen. Lortab has hydrocodone and acetaminophen. Hydrocodone is derived from thebaine and codeine. Dibydrocodeine is derived from codeine and is a strong cough suppressant.
The only difference you might is if you just happen to respond to one better than the other. Many people respond differently to pain medications, so it may just be something that you should figure out with your doctor through trial and error.
In the meantime, these articles about pain medication issues may help:
The consequence of long-term opioid use
The Most Common Reasons that the Pain is Getting Worse