Generic Name: OXYCODONE/ACETAMINOPHEN - ORAL Pronounced: (OX-i-KOE-done/a-SEET-a-MIN-oh-fen) Oxycodone-Acetaminophen Oral Precautions
See also Warning section.
Before taking this medication, tell your doctor or
pharmacist if you are allergic to it; or to other narcotics (such as morphine,
codeine); or if you have any other allergies. This product may contain inactive
ingredients, which can cause allergic reactions or other problems. Talk to your
pharmacist for more details.
Before using this medication, tell your doctor or
pharmacist your medical history, especially of:
brain disorders (such as head injury, tumor,
breathing problems (such as asthma, sleep apnea, chronic
obstructive pulmonary disease-COPD)
mental/mood disorders (such as confusion,
personal or family history of regular use/abuse of
stomach/intestinal problems (such as blockage...
It's not unusual for people living with chronic pain to also be dealing with some depression and/or anxiety . But if you're taking an opioid like oxycodone for the pain and also taking an herbal supplement containing St. John's Wort, you may unknowingly be reducing the effectiveness of your pain medication. A small study in Finland found that when St. John's Wort and oxycodone were taken together, the plasma concentration of oxycodone decreased by 50 percent and its half-life (the time it takes for half the drug to be elimitated from the body) was shortened by 27 percent. The reason for the significant decrease in oxycodone's effectiveness may lie in the fact that St. John’s wort is a well-known to induce CYP450 liver enzymes, which play an important role in the metabolism of many opioids. Although oxycodone was the only opioid tested, it would be logical to think that other opioids which are metabolized through the CYP450 pathways might be similarly...
I took a oxycodone 5mg and 15 min later was given a toradol shot. Is this safe? Amy.
There are no significant interactions between these two medications to make the combination unsafe.
That said, it doesn't mean they're safe for you. It depends on more than those two medications. It also depends on all other medications you're taking and any medical issues you may have. Hopefully, you remembered to tell the doctor who ordered the Toradol about the oxycodone, and he or she considered that before ordering the Toradol.
Good luck, John Claude Krusz and Teri Robert
If you need help finding a Migraine and headache specialist, visit our listing of Patient Recommended Specialists .
About Ask the Clinician :
Dr. Krusz is a recognized expert in the fields of headache and Migraine treatment and pain treatment. Each week, he and Le...
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