Generic Name: IBUPROFEN/OXYCODONE 400 MG/5 MG - ORAL Pronounced: (eye-byou-PRO-fen/ox-ee-KOH-doan) Ibuprofen-Oxycodone Oral Precautions
Before taking this medication, tell your doctor or
pharmacist if you are allergic to oxycodone or ibuprofen; or to other narcotic
pain relievers (such as codeine, hydrocodone); or to aspirin or other NSAIDs
(such as naproxen, celecoxib); or if you have any other allergies. This product
may contain inactive ingredients, which can cause allergic reactions or other
problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or
pharmacist your medical history, especially of:
intestinal/bowel disorders (such as paralytic ileus,
infectious diarrhea, colitis, blockage)
recent heart bypass surgery (CABG)
bleeding/blood-clotting disorders (such as hemophilia,
vitamin K deficiency, low platelet count)
It's not unusual for people living with chronic pain to also be dealing with some depression and/or anxiety . But if you're taking an opioid like oxycodone for the pain and also taking an herbal supplement containing St. John's Wort, you may unknowingly be reducing the effectiveness of your pain medication. A small study in Finland found that when St. John's Wort and oxycodone were taken together, the plasma concentration of oxycodone decreased by 50 percent and its half-life (the time it takes for half the drug to be elimitated from the body) was shortened by 27 percent. The reason for the significant decrease in oxycodone's effectiveness may lie in the fact that St. John’s wort is a well-known to induce CYP450 liver enzymes, which play an important role in the metabolism of many opioids. Although oxycodone was the only opioid tested, it would be logical to think that other opioids which are metabolized through the CYP450 pathways might be similarly...
I took a oxycodone 5mg and 15 min later was given a toradol shot. Is this safe? Amy.
There are no significant interactions between these two medications to make the combination unsafe.
That said, it doesn't mean they're safe for you. It depends on more than those two medications. It also depends on all other medications you're taking and any medical issues you may have. Hopefully, you remembered to tell the doctor who ordered the Toradol about the oxycodone, and he or she considered that before ordering the Toradol.
Good luck, John Claude Krusz and Teri Robert
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About Ask the Clinician :
Dr. Krusz is a recognized expert in the fields of headache and Migraine treatment and pain treatment. Each week, he and Le...
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