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My husband has had an array of medical issues since 2000. He has polycystic kidney disease for which he received a kidney transplant in 2005. Due to an untreated bacterial infection (most likely from the transplant surgery), he contracted bacterial endocarditis and had his aortic valve replaced with an artificial valve shortly thereafter. In 2006, he had a massive subdural hematoma, the cause of which is uncertain. He had a craniotomy, and although not expected to survive, has recuperated and is doing amazingly well except for one thing. Throughout these ongoing problems, he resisted taking narcotic pain medications and opted to take Tylenol to treat his pain. He was fearful he would become addicted to the narcotics and ironically, has become addicted to Tylenol instead. This has resulted in a severe case of rebound headaches and has been going on for years.
He takes Tylenol every six hours all day and still has horrific headaches that ...
What exactly is a "black box" warning? Simply put, it's the strongest warning that the U.S. Food and Drug Administration (FDA) can require on a drug's packaging. The FDA requires the black box warning when studies suggest a drug can cause a serious or life-threatening side effect. The text of the warning is set apart from other information in a black box, so that doctors, pharmacists, and patients can easily see it. What did the FDA advisory panel recommend? The FDA itself hasn't made a decision about acetaminophen, but an FDA advisory panel has made 10 recommendations concerning the drug. Among those recommendations, the panel voted to remove acetaminophen-containing painkillers such as Vicodin, Tylenol 3, and Percocet from the nation's formularies. It also voted in favor of removing all acetaminophen-containing prescription drugs from the market. But the panel voted to keep over-the-counter (OTC) pills that combine acetaminophen and other ingredients, su...
Alternative Names Tylenol overdose; Paracetamol overdose References Goldfrank LR, ed. Goldfrank's Toxicologic Emergencies . 8th ed. New York, NY: McGraw Hill; 2006. American Association of Poison Control Centers. Practice Guideline: Acetaminophen Poisoning: an Evidence-Based Consensus Guideline for Out-of-Hospital Management. Clinical Toxicology , 2006, Vol. 44; pp. 118
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