We've known for a long time that if you're going to stop taking opioids, it's usually best to taper off gradually to prevent severe withdrawal symptoms. But now, there's another very good reason not to abruptly stop taking opioid medications – it can actually increase your sensitivity to pain. A recent study conducted by the Department of Neurophysiology at the Center for Brain Research at the Medical University of Vienna in Austria has found that the sudden withdrawal of opioids leads to the long-term activation of pain impulses being sent to the brain. It creates a kind of memory trace in the pain system. They knew that sustained pain can set up a cycle of increased pain sensitivity, but the researchers were surprised to discover that the abrupt withdrawal of opioids does something very similar by increasing the concentration of calcium ions in the nerve cells of the spinal cord. On the positive side, the research team also discovered that i...
Many people are afraid of what is going to happen to them if they suddenly stop taking pain medications that contain hydrocodone, oxycodone, hydromorphone, oxymorphone, fentanyl, methadone, and buprenorphine. Feeling sick and off balance when one suddenly stops using or doing something is not exclusive to the opioid medications, but opioid withdrawals are the most common form of withdrawal symptoms facing Americans today. Let’s answer some questions that might be on your mind.
What are withdrawals?
Withdrawal symptoms are what your body feels when something that is used or done is suddenly stopped. Your mind starts screaming, “Hey, what just happened here?! I was kind of used to that and I want it back!” This physical feeling can occur if you suddenly stop drinking coffee, stop exercising or stop taking pills. If you suddenly stop something, you might feel some withdrawal symptoms.
Will I feel withdrawals if I stop taking my pills?
If you are taking y...
How long does withdrawal from Zoloft take, and are there any serious side effects that will damage the brain? As far as we know, SSRI withdrawal does not cause permanent damage. But it feels like a bad flu, so it's not fun. The withdrawal is based on two factors: the half-life of the drug and the "potency" of the drug. The short half-life drugs such as Paxil tend to produce worse withdrawal than longer half-life drugs, such as Prozac. Many psychiatrists take advantage of the long half-life of Prozac and prescribe a single dose to treat withdrawal from the other SSRIs. Importantly, there is cross-coverage from other drugs. Stopping Paxil cold will produce withdrawal, but switching Paxil to Zoloft, for example, should protect you from it. In addition, this withdrawal effect is (mostly) limited to serotonergic antidepressants. Wellbutrin is not expected to have this effect.
You should knowAnswers to your question are meant to provide general health information but should not replace medical advice you receive from a doctor. No answers should be viewed as a diagnosis or recommended treatment for a condition. Content posted by community members does not necessarily reflect the views of Remedy Health Media, which also reserves the right to remove material deemed inappropriate.