Some studies have shown that, although Alzheimer's disease and Parkinson's disease are distinct neurological disorders, as many as 25 percent of patients with Alzheimer's develop Parkinson's-like symptoms, and some Parkinson's patients develop signs of Alzheimer's disease. Having known a woman who entered a nursing home with Parkinson's and was later found to have Alzheimer's, I've been curious about this combination. After reading "Living Well With Parkinson's Disease: What Your Doctor Doesn't Tell You...That you Need to Know" by Gretchen Garie and Michael J. Church, co-founders of Movers and Shakers, with Winifred Conkling, I was grateful to the authors for making the educational experience so interesting. I'll admit that I always feel a little put off by books that use "What your doctor doesn't know" in the title, because I feel it's a bit gimmicky, but I'm glad I didn't let that stop me....
Q: I have been diagnosed with degenerative joint disease. I understand this is the same as osteoarthritis . It is primarily in my hips and knees. I am considering going into an upper flat. Is stair climbing beneficial or detrimental to the OA? A: Osteoarthritis is a synonym for degenerative joint disease. People in their 50s and '60s will frequently develop bony nodules over the small joints of the fingers (Heberden's and Bouchard's nodes) which are usually painless, though unsightly. These nodules are frequent markers of osteoarthritis, promising the possibility of joint involvement in other parts of the body. Although nobody knows what constitutes genetic risk factors for the development of osteoarthritis, a large number of people who have undergone trauma to the large weight-bearing joints (football injuries, falls, motor vehicle accidents, surgery) will lose cartilage over time. Cartilage serves as a protective tissue between adjacent long bones, and when lost through...
Spongy degeneration of the brain; Aspartoacylase deficiency
Genetic counseling is recommended for people who want to have children and have a family history of Canavan disease. Counseling should be considered if both parents are of Ashkenazi Jewish descent. For this group, DNA testing can almost always tell whether one or both parents is a carrier.
A diagnosis may be made before the baby is born (prenatal diagnosis) by testing the amniotic fluid .
Rezvani I. Defects in metabolism of amino acids. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF. Nelson Textbook of Pediatrics . 18th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 85.
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