Alzheimer's disease is a degenerative disease of the brain. Because of this the appearance of the brain changes dramatically as the disease progresses.
Alzheimer's disease (AD) most frequently occurs in older people. But even the ‘normal' brain undergoes changes during our lifetime. The brain weighs around 350 grams at birth and increases to around 1,375 grams (about 3 pounds) by the age of 20. In fact the brain quadruples in size in the first three years of life. Then things begin to deteriorate! Brain weight starts to decline between the ages of 45 and 50 years. The brain decreases by about 11 per cent from its maximum weight in early adulthood.
In the older brain tissue loss is most obvious on its surface. There is unmistakable shrinkage in the natural convolutions in brain tissue. Changes are most marked in the forebrain and less so in the cerebellum (the area at the back of the brain mainly responsible for balance and dexterity of movement).
Q: I have been diagnosed with degenerative joint disease. I understand this is the same as osteoarthritis . It is primarily in my hips and knees. I am considering going into an upper flat. Is stair climbing beneficial or detrimental to the OA? A: Osteoarthritis is a synonym for degenerative joint disease. People in their 50s and '60s will frequently develop bony nodules over the small joints of the fingers (Heberden's and Bouchard's nodes) which are usually painless, though unsightly. These nodules are frequent markers of osteoarthritis, promising the possibility of joint involvement in other parts of the body. Although nobody knows what constitutes genetic risk factors for the development of osteoarthritis, a large number of people who have undergone trauma to the large weight-bearing joints (football injuries, falls, motor vehicle accidents, surgery) will lose cartilage over time. Cartilage serves as a protective tissue between adjacent long bones, and when lost through...
Spongy degeneration of the brain; Aspartoacylase deficiency
Treatment mostly aims to ease the symptoms of the disease. Lithium and other drugs are being investigated.
Additional information and resources are available from:
Canavan Foundation: www.canavanfoundation.org
Jacob's Cure: www.jacobscure.org
With Canavan disease, the central nervous system breaks down. Patients are likely to become disabled.
Death often occurs before 18 months of age. However, some patients live until they are teenagers or, rarely, young adults.
This is often a fatal disorder. It includes severe disabilities such as:
Inability to walk
Calling your health care provider
Call your health care provider if your child has any symptoms of Canavan disease.
You should knowAnswers to your question are meant to provide general health information but should not replace medical advice you receive from a doctor. No answers should be viewed as a diagnosis or recommended treatment for a condition. Content posted by community members does not necessarily reflect the views of Remedy Health Media, which also reserves the right to remove material deemed inappropriate.