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Sunday, March 25, 2012 jakim, Community Member, asks

Q: Can I take Vicodin and Zanaflex? Taking Zanaflex for neck spasms and want to take a vicodin for the pain.

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Answers (1)
Cort, Health Guide
3/25/12 6:26pm

You should talk to your doctor about this. According to a Drug Interactions Checker at these two drugs have a 'moderate' effect with each other.  This is because both have sedating properties. Here's the warning. 


MANAGEMENT: Use of tizanidine with other substances that commonly cause sedation should be approached with caution, particularly in elderly or debilitated patients. Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.


The Drug Checker also notes that it may not catch all drug interactions and that you should always check with your doctor.

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By jakim, Community Member— Last Modified: 03/25/12, First Published: 03/25/12