• Debbie Debbie
    May 10, 2009
    Percocet and Coumadin
    Debbie Debbie
    May 10, 2009

    My dad is on coumadine for his heart condition and now has severe back pain and was given percocet. Is it ok for him to take it?



  • Karen Lee Richards
    Health Guide
    May 12, 2009
    Karen Lee Richards
    Health Guide
    May 10, 2009

    Percocet is a combination of oxycodone and acetaminophen.  When you look at the dosage, the first number is usually the amount of oxycodone and the second number is the amount of acetaminophen.  The acetaminophen dosage should be either 325, 500 or 650. 


    When combining Coumadin and Percocet, it's recommended that you keep the total amount of acetaminophen to less than 2,000 mg a day.  Too much acetaminophen can increase the risk of bleeding.  So as long as the total amount of acetaminophen he's getting with the Percocet each day doesn't exceed 2,000 mg, he should be able to take it.  Note:  Be sure to check the ingredients of any over-the-counter medications he might take (like cold and flu preparations) because they often contain acetaminophen and that would need to be counted in his total for the day.


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