Polymyositis is a systemic disease, which means it affects the whole body. Symptoms include:
Muscle weakness in the proximal muscles (shoulders, hips, etc.) that makes it difficult to raise the arms over the head, get up from a sitting position, or climb stairs
Problems with the voice (caused by weak throat muscles)
Shortness of breath
Patients may also have:
Loss of appetite
A similar condition called dermatomyositis causes a reddish-purple or red rash on the face or body.
Signs and tests
Muscle weakness and tenderness can be signs of polymyositis. A rash is a sign of a similar condition, dermatomyositis.
Tests may include:
Autoimmune antibodies and inflammation tests
MRI of affected muscles
Female athletes have many more injuries to the anterior cruciate ligament (ACL) of the knee than male athletes. Studies have shown that women college soccer and basketball players have two to four times as many ACL injuries as men. And among professional basketball players, women have 10 times more ACL injuries than men. ACL injuries are especially serious. They often require surgery and intense rehabilitation. And they force many injured athletes to give up their sports. No one is exactly sure why women suffer so many ACL injuries. It is known that the thigh muscles help stabilize the knee joint during start-and-stop sports like basketball and soccer. These researchers tested the muscle activity of male and female college athletes during exercise. They wanted to see if the thigh muscles worked differently when doing intense extension and flexion exercises. The results showed that the men's quadriceps muscles (in the front of the thigh) produced much more force than the women's. But t...
Injury to the anterior cruciate ligament (ACL) in the knee is really more than just a torn ligament. Along with damage to the ligament comes weakness of the quadriceps muscle. The quadriceps is the large muscle that comes down over the front of the thigh from the hip to the knee. Scientists are trying to unlock the puzzle of this muscle weakness. The muscle isn't wasting away, a condition called atrophy . So what could be causing this weakness? Is there some way that the ligament signals the muscle to contract in a normal knee? What other changes occur after a ligament is torn or damaged that could affect the muscle? Researchers at the University of Tokyo in Japan set out to answer these questions. They found signals that form a complete loop from knee joint to ligament to muscle. This is called afferent feedback . Before the experiment, scientists thought that damage to the ACL alters this loop. Decreased signals to the muscle cause the weakness. To prove this, they used vibration to the ...
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