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Last week, the United States Food and Drug Administration (FDA) made it official: Lyrica, the trade name of the Pfizer drug pregabalin, was approved as a treatment for fibromyalgia . This is the first drug to be specifically approved for the treatment of fibromyalgia, this based on the findings that it reduced pain and improved the ability to perform the activities of daily living in a significant number of patients suffering from this chronic pain syndrome. However, an FDA official cautioned that not all patients experienced benefit from Lyrica. Lyrica was already approved for the treatment of other chronic pain disorders , including pain associated with shingles and diabetic neuropathy. This additional approval was based upon two large studies which concluded that benefit could be had with daily dosages of Lyrica in the 300 mg to 450 mg range. The use of Lyrica resulted in an increased time to loss of therapeutic response compared to placebo over a six month p...
A case was recently reported of a 70-year-old man who developed rhabdomyolysis after his Lyrica (pregabalin) dosage was increased and he was also given Zocor (simvastatin), a statin drug usually given for high cholesterol. Rhabdomyolysis is the breakdown of muscle fibers that leads to the release of muscle fiber contents (myoglobin) into the bloodstream, which is harmful to the kidneys and often causes kidney damage.
When he arrived at the emergency room, the man was mentally disoriented, he was unable to stand up, all four extremities were twitching and he had slurred speech. Other symptoms of rhabdomyolysis may include:
Dark, red or cola colored urine
Decreased urine production
Muscle stiffness or aching
Weakness of affected muscles
Unintentional weight gain
Statin drugs are known to sometimes cause rhabdomyolysis. Lyrica is not generally recognized as a cause of rhabdomyolysis, although in t...
Q. My breast swelled up and was hot and painful to the touch. My doctor treated me for mastitis, but it turned out to be inflammatory breast cancer. I think other women should be aware that not all breast cancers start with a lump. A. That’s right. Inflammatory breast cancer does look a lot like mastitis, an infection of the breast that can have many causes. Mastitis is more common when you’re breast-feeding; and some women have a lifelong proclivity to bouts of mastitis. But if you’re experiencing a swollen, hot, painful, red breast for the first time, ask your doctor to carefully consider inflammatory breast cancer, and to test for it. Previous Breast Cancer Symptom: Lump Under Arm Back to Start of Illustrated Symptom FAQs
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