A case was recently reported of a 70-year-old man who developed rhabdomyolysis after his Lyrica (pregabalin) dosage was increased and he was also given Zocor (simvastatin), a statin drug usually given for high cholesterol. Rhabdomyolysis is the breakdown of muscle fibers that leads to the release of muscle fiber contents (myoglobin) into the bloodstream, which is harmful to the kidneys and often causes kidney damage.
When he arrived at the emergency room, the man was mentally disoriented, he was unable to stand up, all four extremities were twitching and he had slurred speech. Other symptoms of rhabdomyolysis may include:
Dark, red or cola colored urine
Decreased urine production
Muscle stiffness or aching
Weakness of affected muscles
Unintentional weight gain
Statin drugs are known to sometimes cause rhabdomyolysis. Lyrica is not generally recognized as a cause of rhabdomyolysis, although in t...
Has anyone tried Lyrica, Diltiazem and toradol, the dr has me on this and I am very dopey. I have had migranes since I was young. I have just had decompression surgery for chiari malformation. The migranes are now very bad. My family Dr. has me on Lyrica 75 mg 2 times a day, sandoz diltiazem 120 mg once a day and toradol 10 mg 4 times a day. I am very sleepy and dopey, has anyone else tried these? Any suggestions would be appreciated. thanks , Michelle.
Diltiazem is a calcium channel blocker initially developed for heart issues and hypertension. It has since been found to be effective in preventing Migraine. One potential side effect is drowsiness, but that usually stops as your body becomes accustomed to it.
The prescribing information for Lyrica actually carries this warning: " LYRICA may cause dizziness and somnolence and impair patients’ ability to drive or operate machinery ." The DEA has actually listed...
Definition Joint swelling is the buildup of fluid in the soft tissue surrounding the joint. Alternative Names Swelling of a joint Considerations Joint swelling may occur along with joint pain . The swelling may cause the joint to appear larger or abnormally shaped. Joint swelling can cause pain or stiffness. After an injury, swelling of the joint may mean you have a broken bone or a tear in the muscle tendon or ligament. Many different types of arthritis may cause swelling, redness, or warmth around the joint. An infection in the joint can cause swelling, pain, and fever. Common Causes Joint swelling may be caused many different things, including: Ankylosing spondylitis Gout Osteoarthritis Pseudogout Psoriatic arthritis Reactive arthritis Rheumatoid arthritis Septic arthritis Systemic lupus erythematosus
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