• Arlene Arlene
    December 12, 2008
    why am I itching after taking pain killers, oxycodone, hydrocodoneand mepiridine/What is safe for me
    Arlene Arlene
    December 12, 2008

FROM OUR EXPERTS

  • Karen Lee Richards
    Health Guide
    December 13, 2008
    Karen Lee Richards
    Health Guide
    December 12, 2008

    I hope you'e not saying that you're taking all three medications at the same time since all are opioids and taking that many at once could result in an overdose. 

     

    As for the itching, there are two types of itching that sometimes occur when taking opioids.  One is an allergic-type reaction caused by a histamine release and can be relieved by taking an antihistamine like Benadryl.  The other is caused when the "itch gene" (called the gastrin-releasing peptide receptor or GRPR) is stiumlated.  This type of itch does not respond to antihistamines. 

     

    If your itching continues and does not get better by taking Benadryl, call your doctor.  You may need to try another type of pain reliever.

     


FROM OUR COMMUNITY

  • Helen39 April 20, 2009
    Helen39
    December 12, 2008

    Oops! Please be aware everyone that Benadyl will make you even more sleepy than you are on the other drugs. Claradyne and Telfast non drowsy didn't work. Helen39

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  • Helen39 April 20, 2009
    Helen39
    December 12, 2008

    I have asked the same question Arlene and will give Benadryl a try. Unlike the 2nd answer I do not get used to these drugs but after taking them for a few months I start to react like you have. Apparently it is a common side effect to these opiates.

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  • tystick December 13, 2008
    tystick
    December 12, 2008

    Because your not used to them.I used to itch too. also when my daughter got her wisdom theeth out they gave her oxycodone. her first question is why am I itching.?I liked the other ladies comment.Maybe it is a itch geene and they just trigger it. But you hear that alot ,about people starting to take these kind of meds

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