Yesterday the U.S. Food and Drug Administration announced that it is asking manufacturers of prescription combination products that contain acetaminophen to limit the amount of acetaminophen to no more than 325 mg (milligrams) in each tablet or capsule. Acetaminophen is probably best known by the brand name Tylenol. Outside the U.S., it is often called paracetamol and on prescriptions it may be labeled as APAP (For example, hydrocodone APAP). The drugs most affected by this action are opioid pain relievers that are combined with acetaminophen like codeine (Tylenol #3), hydrocodone (Vicodin, Lortab) and oxycodone (Percocet). “FDA is taking this action to make prescription combination pain medications containing acetaminophen safer for patients to use,” said Sandra Kweder, M.D., deputy director of the Office of New Drugs in FDA’s Center for Drug Evaluation and Research (CDER). “Overdose from prescription combination products containing acetaminop...
My daughter who is 15 has been suffering from daily migraines since March 2008. She sees a neurologist. They first put her on Topomax-nothing changed. She has now been on HYDROCO/APAP for a month and still has excruciating pain daily. What should we do next? Her grades are suffering and she does not sleep well either. Maureen .
There are several issues here.
The hydrocodone and acetaminophen may well be making matters worse by causing medication overuse headaches (MOH), aka rebound. Pain medications need to be limited to two or three days a week to avoid MOH. For more information on this, please see Medication Overuse Headache - When the Remedy Backfires . Another problem MOH can cause it that it can keep Migraine preventive medications from working.
How long did she try the Topamax? It can take up to three months to know if that type of medication is going to w...
Some chronic pain patients, particularly in Florida, are finding it difficult to fill their oxycodone prescriptions at their local pharmacies. Pharmacists are telling them they don't have any oxycodone. But is that true? Maybe, maybe not.
Technically, according to the DEA, there is no shortage of oxycodone. Pharmaceutical companies are producing it at normal levels. What is in short supply are pharmacists who are willing and able to fill your prescription.
Here's the Story...
Florida has had a huge problem with unscrupulous doctors prescribing and often also dispensing large quantities of opioids, primarily oxycodone, from storefront operations commonly called “pill mills.” According to a 2011 NPR report, doctors in Florida were prescribing 10 times more oxycodone than all the other U.S. states combined.
In an effort to curb this oxy epidemic, the DEA began cracking down not only on Florida doctors, but also on pharmacies and wholesale drug dis...
You should knowAnswers to your question are meant to provide general health information but should not replace medical advice you receive from a doctor. No answers should be viewed as a diagnosis or recommended treatment for a condition. Content posted by community members does not necessarily reflect the views of Remedy Health Media, which also reserves the right to remove material deemed inappropriate.