This is the third in our series on medical marijuana for bipolar. In the first piece , we made a conditional case for marijuana to treat bipolar, with some major provisos. The second piece compared the risk/benefits of medical marijuana with prescription drugs.
In this installment, we look at the endocannabis system that marijuana acts upon.
Endocannabinoids (ECs) are naturally occurring compounds throughout the brain and body that regulate cellular signaling and cellular maintenance. They function in a similar fashion to neurotransmitters such as serotonin and dopamine, except they travel backward, against the flow, from the postsynaptic cell to the presynaptic cell.
At the presynaptic cell, the ECs dock to CR1 and CR2 cannabinoid receptors and release their chemical messages. One of the effects may be to inhibit the release of certain neurotransmitters from the presynaptic cell back to the postsynaptic cell.
In effect, the postsynaptic cell restricts the f...
Tremor, or uncontrolled shaking, is a highly disabling symptom of multiple sclerosis which is often associated with a more advanced disease course. Tremor, an involuntary, rhythmic, muscle movement caused by repetitive contraction and relaxation of paired muscle groups, has long been recognized as a feature of MS. The French neurologist Dr. Jean-Martin Charcot (1825-1893) categorized it with nystagmus and scanning speech (Rascol, 1982).
A study published in the open-access journal Tremor and Other Hyperkinetic Movements reviewed recent advancements in the understanding of tremors in MS. The review explores the prevalence and clinical features of tremors in MS, including physical cause of tremors, and treatment methods, including surgery and/or prescription medications.
Reviewers searched MEDLINE with the terms “multiple sclerosis” and “tremor,” published between January 1966 and May 2012. My own search revealed articles dati...
("pot") intoxication is the euphoria, relaxation, and sometimes undesirable side effects that can occur when people use marijuana.
Marijuana is the most commonly used illegal drug in the United States. The drug is usually smoked, but is sometimes eaten.
Today, there are more than 12 million marijuana users in the United States and more than 300 million regular users worldwide.
Cannabis intoxication; Intoxication - marijuana (cannabis); Pot; Mary Jane; Weed; Grass; Cannabis
Causes, incidence, and risk factors
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