FROM OUR EXPERTS
Researchers at the Fisher Center for Alzheimer’s Disease Research at The Rockefeller University have published the results of their recent study, which showed that non-steroidal anti-inflammatory drugs (NSAIDs) reduced the effectiveness of selective serotonin reuptake inhibitor (SSRI) antidepressants.
NSAIDs include over-the-counter medications like ibuprofen, aspirin and naproxen as well as prescriptions drugs such as Celebrex, Daypro, diclofenac, etodolac, ketoprofen, meloxicam, Mobic, Naprosyn, Relafen, Toradol, Voltaren, etc.
You may be wondering what this study has to do with chronic pain. Antidepressants are sometimes prescribed as a treatment for chronic pain because they help increase serotonin, which is important for pain modulation. If NSAIDs prevent antidepressants from being effective for depression, they may also interfere with the ability of antidepressants to reduce pain. Study Design and Results Scientists first tested their theory on mice...
Generic Name: SUMATRIPTAN/NAPROXEN SODIUM - ORAL Pronounced: (SOO-ma-TRIP-tan/na-PROX-en) sumatriptan-Naproxen Oral Precautions
See also How to Use section.
Before taking this product, tell your doctor or pharmacist
if you are allergic to naproxen or to sumatriptan; or to aspirin or other
NSAIDs (such as ibuprofen, celecoxib); or if you have any other allergies. This
product may contain inactive ingredients, which can cause allergic reactions or
other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain
medical conditions. Before using this medicine, consult your doctor or
pharmacist if you have:
aspirin-sensitive asthma (a history of worsening breathing
with runny/stuffy nose after taking aspirin or other NSAIDs)
heart disease (such as chest pain, previous heart
decreased blood flow in the brain (such as previous stroke,
transient ischemic attack)
Definition Ibuprofen is a type of nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen overdose occurs when someone accidentally or intentionally takes more than the normal or recommended amount of this medication. See also: Pain medicine This is for information only and not for use in the treatment or management of an actual poison exposure. If you have an exposure, you should call your local emergency number (such as 911) or the National Poison Control Center at 1-800-222-1222. Alternative Names Advil overdose; Nuprin overdose; PediaProfen overdose; Rufen overdose; Motrin overdose Poisonous Ingredient Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) that is sold over-the-counter and by prescription. Where Found Advil Medipren Midol Motrin Nuprin Pamprin IB PediaProfen Rufen Note: This list may not be all-inclusive.
You should know
Answers to your question are meant to provide general health information but should not replace medical advice you receive from a doctor. No answers should be viewed as a diagnosis or recommended treatment for a condition. Content posted by community members does not necessarily reflect the views of Remedy Health Media, which also reserves the right to remove material deemed inappropriate.