Although triptans are a marked improvement over previous treatment options, many Migraineurs have not been fully satisfied with their results. Some do not achieve full relief from triptans, and the recurrence of Migraines within 24 hours of the first dose has been common. With the patents on sumatriptan nearing their expiration, both generics of the current forms – injections, tablets, and nasal spray – and other medications containing sumatriptan are now in development and testing. The results involving Trexima, one such medication that is a combination of sumatriptan and naproxen, have now been published. Read Study Finds Sumatriptan-Naproxen Combination More Effective against Migraine Attacks .
I am a bit confused about MOH. Can naproxen sodium (Aleve, etc) cause it? I don't see it listed among the usual suspects. I take naproxen as my first line defense against my chronic daily migraines. It is, thankfully, sometimes effective and I'd hate to give it up. Thanks. Elizabeth.
NSAIDs such as naproxen sodium should not be taken daily. A recent study confirmed that:
NSAIDs were actually associated with a decreased risk of transformed Migraine ONLY for Migraineurs with fewer than 10 - 14 Migraine days per month. This would serve to confirm that NSAID use should be restricted to no more than two or three days per week and should NOT be used for Migraine prevention.
For more information on this, please see Medication Overuse Headache - When the Remedy Backfires .
It's entirely possible that daily use of naproxen sodium is making things worse for you. The better option is to work with your doctor t...
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