Definition Sciatica refers to pain, weakness, numbness, or tingling in the leg. It is caused by injury to or compression of the sciatic nerve. Sciatica is a symptom of another medical problem, not a medical condition on its own. Alternative Names Neuropathy - sciatic nerve; Sciatic nerve dysfunction Causes, incidence, and risk factors Sciatica occurs when there is pressure or damage to the sciatic nerve. This nerve starts in the spine and runs down the back of each leg. This nerve controls the muscles of the back of the knee and lower leg and provides sensation to the back of the thigh, part of the lower leg, and the sole of the foot. Common causes of sciatica include: Piriformis syndrome (a pain disorder involving the narrow piriformis muscle in the buttocks) Slipped disk Degenerative disk disease Spinal stenosis Pelvic injury or fracture Tumors
References Apkarian AV, Sosa Y, Sonty S, Levy RM, Harden RN, Parrish TB, et al. Chronic back pain is associated with decreased prefrontal and thalamic gray matter density. J Neurosci . 2004;24(46):10410-10415. Fairbank J, Frost H, Wilson-MacDonald J, Yu LM, Barker K, Collins R; Spine Stabilisation Trial Group. Randomised controlled trial to compare surgical stabilisation of the lumbar spine with an intensive rehabilitation programme for patients with chronic low back pain: the MRC spine stabilisation trial. BMJ . 2005;330(7502):1233. Filler AG, Haynes J, Jordan SE, Prager J, Villablanca JP, Farahani K, et al. Sciatica of nondisc origin and piriformis syndrome: diagnosis by magnetic resonance neurography and interventional magnetic resonance imaging with outcome study of resulting treatment. J Neurosurg Spine . 2005;2(2):99-115. Freeman BJ, Fraser RD, Cain CM, Hall DJ, Chapple DC. A randomized, double-blind, controlled trial: intradiscal electrothermal therapy versus placebo for the treatment...
I have always had a love-hate relationship with prednisone.
I don’t like to be on it. I was miserable when I was on it all the time, but not being on it, my pain significantly increased.
I was really stubborn, though, and when I was on prednisone on an “as needed” basis, I probably only took it once a month.
The last time I was at my rheumatologist’s, he suggested going back on steroids full time, but rather than putting me back on prednisone, he suggested that I try methylprednisolone.
He told me that while prednisone is the go-to, default steroid in the United States, methylprednisolone is the default in Europe.
You might think a steroid is a steroid , because that is sort of what I thought, too, but my experience suggests otherwise.
A cursory search of PubMed, using the search term “prednisone” reveals 43,591 results and using the search term “methylprednisolone” reveals...
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