Vascular spasms temporary limit blood flow to tissue supplied by that vessel. The most common symptom is pain. Other symptoms are caused by lack of proper circulation and will vary depending on the specific organ affected:
When the spasm affects circulation in a limb, there may be pallor and a sensation of cold in that arm or leg. Limb function and movement will be impaired.
When the spasm affects circulation in the heart, there may be symptoms similar to a heart attack and irregular heartbeats. Other names for chest pain resulting from vascular spasm are Prinzmetal's angina and variant angina.
Signs and tests
These vary depending on the affected organ.
Definition Coronary artery spasm is a temporary, sudden narrowing of one of the coronary arteries (the arteries that supply blood to the heart). The spasm slows or stops blood flow through the artery and starves part of the heart of oxygen-rich blood. Alternative Names Variant angina; Angina - variant; Prinzmetal's angina Causes, incidence, and risk factors The spasm often occurs in coronary arteries that have not become hardened due to plaque buildup ( atherosclerosis ). However, it also can occur in arteries with plaque buildup. A contraction (squeezing) of muscles in the artery wall causes these spasms in the arteries. The contraction occurs in just one area of the artery. The coronary artery may appear normal during angiography , but it does not function normally. Coronary artery spasm affects approximately 4 out of 100,000 people. About 2% of patients with angina have coronary artery spasm. Coronary artery spasm occurs most commonly in people who smoke or who have high cholesterol or high ...
This study continues the work already done investigating the use of botulinum type A toxin (Botox A) for relief of muscle pain. A specific Botox agent called Dysport ® was used in patients with upper back pain. Dysport® has a much higher biologically active dosage compared to Botox®. All patients had been diagnosed with a condition called myofascial pain syndrome (MPS). MPS is described as chronic muscle pain from shortened or contracted muscles. Trigger points (TrPs) are often part of the clinical picture. TrPs are areas of hyperirritable spots. When pressed or stimulated, TrPs cause a predictable pain pattern. Patients included were men and women between the ages of 18 and 70 years. All had MPS with at least 10 TrPs present in the neck or upper back. Symptoms had been reported for at least six months. Each patient was given a single injection of Dysport® into the 10 most painful TrPs. Pain level after five weeks was the main result measured. Change in pain intensity and number of pain-...
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