Definition Acute tubular necrosis is a kidney disorder involving damage to the tubule cells of the kidneys, resulting in acute kidney failure . Alternative Names Necrosis - renal tubular; ATN; Necrosis - acute tubular Causes, incidence, and risk factors Acute tubular necrosis (ATN) is caused by lack of oxygen to the kidney tissues (ischemia of the kidneys). The internal structures of the kidney, particularly the tissues of the kidney tubule, become damaged or destroyed. ATN is one of the most common structural changes that can lead to acute renal failure. ATN is one of the most common causes of kidney failure in hospitalized patients. Risks for acute tubular necrosis include: Blood transfusion reaction Injury or trauma that damages the muscles Recent major surgery Septic shock or other forms of shock Severe low blood pressure (hypotension) that lasts longer than 30 minutes Liver disease and kidney damage caused by diabetes ( diabetic nephropathy ) may make a person more susceptible to the condition. A...
Chronic kidney disease in itself has been found to be an independent predictor for the development of heart disease and is associated with an overall poorer prognosis. This effect occurs throughout the entire spectrum of kidney failure ranging from those with mild kidney disease to even those who have had successful kidney transplants. In one study of a million people with kidney failure who were not yet on dialysis, the risk of developing atherosclerosis was almost 35 times more likely than the risk of needing some type of kidney replacement therapy. In fact, the American National Kidney Foundation, the American College of Cardiology, and the American Heart Association consider people with chronic kidney disease to be at equal risk of a future cardiovascular event when compared to those who have already had a heart attack . Many conditions that confer increased heart disease risk can also lead to chronic kidney damage. Some common examples are high blood pressur...
Parents and doctors beware! Antibiotic use during the first year of life probably does cause asthma!
There is enough research now that we can definitely say probably. General thinking for years has been that if a child has an infection it should be treated with antibiotics. Yet newer evidence is leaning in the direction that while antibiotics cure an acute infection, it may cause asthma later on.
The most recent study was completed by Yale University researchers , and they interviewed women during pregnancy and when the child was 6-years-old. Of the 1,401 studied:
40 percent of infants given just one dose of antibiotics developed childhood asthma and allergies.
70 percent of infants given two rounds of antibiotics developed asthma
These are pretty significant statistics, and they correlate well with past studies like this one completed in 2007 at the University of Manitoba and McGill University in Montreal.
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