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Yes. As well as making folk sick (as in my own case) opiates sometimes have absolutely NO effect at all on some. My own Dr told me of anothr of his patients who is absolutely unmoved by opiates in any way. She is,apparently, doing very well on Prialt(Ziconitide). Unfortunately it is VERY expensive. I tried it to no availe, it made me sick, just like everything else. Mag1

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