Does Lyrica start working on the first time you take it?
...or does it take a while for the drug to build itself up in your system before you feel its effects starting to work? What are normal starting doses and then what are regular doses?
Lyrica generally takes at least a week to start working and can take considerably longer. According to the Lyrica website dosages typically start out at 150 mg/day (in 2-3 divided doses) and patients can work up to 300 mg/day over a week or two. The highest dosage is 600 mg/day but that typically doesn't seem to offer many added benefits.
http://www.pfizer.com/files/products/uspi_lyrica.pdf
http://www.healthcentral.com/chronic-pain/find-drug-68372-73.html
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spinalcordandMSgirl
Monday, July 20, 2009 at 06:48 PM
For me Lyrica started helping immediately, at first I was very drowsy but after a week or so that side effect went away. I was started on 75mg/day and now I am on 150mg twice a day. and have been on it almost a year. It really helped me.
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You may see results immediately but I would not get my hopes up on that happening. Most websites tell you to wait at least 2 weeks to start seeing results. The minor and annoying side effects start subsiding in that timeframe and you should start to see how well things are going.
Dosing varies. I started at 50 mg a day for a week, increasing 50 mg a week until I reached 150 mg ( 50 mg 3x a day). After that, your doctor can adjust the dosing depending on your tolerance and the effective of the medication.
I took Lyrica for the burning pain of my RSD but we were not a good match. The lyrica did help my pain but the side effects for me were too much. It helped me sleep and that also helped with my pain.
I have talked to many lyrica users and I have noticed it is either a miracle drug or a drug from hell for people. It works or it doesn't, very black and white.
Reta
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Lyrica works on the serotonin system and takes 1-12 weeks to reach full effect, if it's going to work.
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Whoever said it's either a miracle drug or the drug from hell is right. For me, it was the drug from hell. I'm told I walked around like a zombie, spoke nonsense all day, and spent hours just staring straight ahead. Worst of all, I have no memory of the 4 weeks I was on it at all, so I can't dispute or confirm the above. If a friend had not called my doctor (I live alone) I am afraid of what might have happened. Please have someone you trust watch you carefully at the beginning. I know this drug has helped many, but I know from my research that my reaction was far from rare and also common with Lyrica's parent drug, Neurontin.
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Lyrica was like a miracle when I started taking it over a year ago. Recently, I have experienced severe foot pain and I feel like I am walking on golf balls. I can only walk for around 10 minutes before I have to sit down and rest my feet. I am seriously wondering if the medicine is creating a backlash with the pain that it originally controlled.
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I suppose that after many doctors for my own MS, then trying to take care of my mom's last days with MS I learned quite a bit. I do know that once she got the Lyrica into her system, she no longer woke up crying in pain.
I'm so happy I found this page and am feeling quite at home with the people and doctors here. Thank you!