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Trembling, restlessness, nervousness, and anxiousness are all most likely to be caused by the steroid (Prednisone).   If the Tylenol #3 was causing trembling, it could be because the Tylenol is damaging the liver. Older individuals are more suseptable to liver toxicity from medications, especially with other health conditions exist. Limiting the daily Tylenol amount is very important in the elderly and monitoring of the liver function with blood test may be advisable. Talk to your doctor about your concerns. Dr. Christina Lasich, MD
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