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ChronicPainConnection.com

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Tuesday, December, 01, 2009
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A blanket statement suggesting that an opiod analgesic has no withdrawal symptoms upon ceasing use is not accurate. My symptoms were not related to menopause as I was in my late 20's at the time of stopping Tramadol, nor were my smptoms resultant of other medication use. Here is some info I dug up which correlates with my own experience: Physical dependence and withdrawal Tramadol is associated with the development of a physical dependence and a severe withdrawal syndrome.[31] Tramadol causes typical opiate-like withdrawal symptoms as well as atypical withdrawal symptoms including seizures. The atypical withdrawal effects are probably related to tramadol's effect on serotonin and norepinephrin reuptake. Symptoms may include anxiety, depression, anguish, severe mood swings, brain "zapps", electric-shock sensations throughout body, pins and needles, sweating, palpitations, restless legs syndrome, sneezing, insomnia, tremors, among others. In most cases, tramadol withdrawal will set in 12 to 20 hours after the last dose, but this can vary. Tramadol withdrawal lasts longer than that of other opioids. It is recommended that patients physically dependent on pain killers take their medication regularly to prevent onset of withdrawal symptoms and this is particularly relevent to tramadol because of its SSRI and SNRI properties, and, when the time comes to discontinue their tramadol, to do so gradually over a period of time that will vary according to the individual patient and dose and length of time on the drug
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