Generic Name: OXYCODONE/ASPIRIN - ORAL Pronounced: (ox-ee-KOH-doan/AS-pir-in) Oxycodone-Aspirin Oral Precautions
Before taking oxycodone with aspirin, tell your doctor or
pharmacist if you are allergic to it; or to other narcotics (such as codeine,
hydrocodone), salicylates (such as salsalate), or nonsteroidal
anti-inflammatory drugs (such as ibuprofen, naproxen, celecoxib); or if you
have any other allergies. This product may contain inactive ingredients, which
can cause allergic reactions or other problems. Talk to your pharmacist for
Before using this medication, tell your doctor or
pharmacist your medical history, especially of:
intestinal/bowel disorders (such as paralytic ileus,
infectious diarrhea, colitis, blockage)
bleeding/blood-clotting disorders (such as hemophilia,
vitamin K deficiency, low platelet count)
stomach problems (such as ulcers, heartburn, stomach
It's not unusual for people living with chronic pain to also be dealing with some depression and/or anxiety . But if you're taking an opioid like oxycodone for the pain and also taking an herbal supplement containing St. John's Wort, you may unknowingly be reducing the effectiveness of your pain medication. A small study in Finland found that when St. John's Wort and oxycodone were taken together, the plasma concentration of oxycodone decreased by 50 percent and its half-life (the time it takes for half the drug to be elimitated from the body) was shortened by 27 percent. The reason for the significant decrease in oxycodone's effectiveness may lie in the fact that St. John’s wort is a well-known to induce CYP450 liver enzymes, which play an important role in the metabolism of many opioids. Although oxycodone was the only opioid tested, it would be logical to think that other opioids which are metabolized through the CYP450 pathways might be similarly...
The drug metformin is not recommended for people with
kidney disease. For this reason, some people think that metformin causes kidney disease. But new evidence
suggests that metformin might actually protect the kidneys.
For many people with type 2 diabetes , metformin is a very
effective drug. In everyone, the liver is a sort of "mother" organ. When blood
glucose (BG) levels go down, the liver releases some glucose into the blood to
make sure all the other organs get enough glucose energy to work properly.
When you eat and your BG levels start going up, the liver
is supposed to stop pushing all this glucose out into the bloodstream.
But for some reason, in people with type 2 diabetes, like
an oversolitous mother, the liver doesn't stop feeding the bloodstream after
meals. "Eat eat!" I can hear it say to a bloodstream already stuffed with
glucose. And this continued release of glucose into the bloodstream after
meals is one reason people with type 2 go high after me...
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