Tuesday, February 09, 2010 MN Gal, Community Member, asks

Q: What pain meds can be used for knee replacement surgery when allergic to codeine?

I have had very adverse reactions when taking codeine, both as pills and in a cough medicine. I am in need of a total knee replacement and have a concern about which pain medicines will work for me with such an aversion to codeine and morphine meds. Reaction I had was to go into a sleep state similar to a coma where I could hear people around me but could not move any part of my body. Family thought I was sleeping but I was clearly awake but could not move any part of my body. Thanks for your input.

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Answers (1)
Cort, Health Guide
2/ 9/10 1:37pm

If you problems with codeine and morphine medications it sounds like all the narcotic drugs may be out since they are all versions of one another. Are you sure you're having a reaction to the narcotic drugs or to the anesthesia drugs given to you during surgery? Did you continue to have this reaction after the surgery or just during the surgery? If it was just during the surgery then it was probably a reaction to the anesthesia drugs. I hope you weren't in pain Yell


If you can't tolerate narcotic drugs there are other drugs that do help with pain; they include anticonvulsants such as Neurontin and Lyrica, antidepressant and anti-anxiety drugs, strong anti-inflammatory drugs as well as relaxation exercises designed to slow down the activity of the pain centers of the brain. 



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By MN Gal, Community Member— Last Modified: 10/21/10, First Published: 02/09/10