FROM OUR EXPERTS
It's confusing. Some doctors tell us to take Migraine abortive medications such as the triptans early in a Migraine attack -- during the aura if you get auras. Others say triptans won't work taken that early, to wait for the headache phase to begin. So, for those of us with Migraine with aura, when IS it best to take triptans? When the aura starts? When the pain starts? Does it even make a difference. Aurora et. al. set out to take a look at those very question. The objective of their study was "To reexamine the efficacy of terminating migraine headache by administration of sumatriptan during the visual-aura phase of the attack." Previous studies have been conflicting and confusing. It has been shown that taking triptans early in the headache phase of a Migraine attack, while the pain is mild and allodynia has not fully developed, increases the success rate of triptans for giving pain-free relief. However, previous data had also shown that taking tript...
Most everyone knows narcotic pain killers like morphine, Percocet, and Vicodin are powerful. Doctors prescribe them with caution because although they relieve pain, they also have some nasty side effects. Addiction being one of those effects. But sometimes physicians are too cautious not realizing that some people require 10 to 40 times the standard dose to get the same effect. Animal studies have confirmed what doctors see in the clinic -- there are some unique differences in patient responsiveness. Scientists have found that the wide variability in how people respond to these drugs might be genetic. And once they discovered this factor, they found more than one genetic trait that is involved. For example, some folks don't have the CYP2D6 enzyme needed to activate the drug. Without this enzyme, the drug isn't metabolized (broken down) and the patient gets no (or very minimal) pain relief. Another problem occurs when P-glycoprotein doesn't function properly. This is the protein that tra...
Generic Name: HYDROCODONE/ACETAMINOPHEN - ORAL Pronounced: (HYE-droe-KOE-done/a-SEET-a-MIN-oh-fen) Vicodin ES Oral Uses
This combination medication is used to relieve moderate to
severe pain. It contains a narcotic pain reliever (hydrocodone) and a
non-narcotic pain reliever (acetaminophen). Hydrocodone works in the brain to
change how your body feels and responds to pain. Acetaminophen can also reduce
How To Use Vicodin ES Oral
See also Warning section.
Read the Patient Information Leaflet if available from
your pharmacist before you start taking this medication and each time you get a
refill. If you have any questions, ask your doctor or
Take this medication by mouth as directed by your doctor.
You may take this drug with or without food. If you have nausea, it may help to
take this drug with food. Ask your doctor or pharmacist about other ways to
decrease nausea (such as lying down for 1 to 2 hours with ...
You should know
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