Question: I have been living with RA since 1991. For the last 5-6 years I have been on Vicodin of various strengths. The Vicodin no longer works, not even taking the edge off of the pain anymore. My doctor is hesitant to give me anything stronger. He says the next step is narcotics and there is the danger of addition. I frankly don't care anymore. So what if I get addicted to something? At least I'll have some kind of a life, be able to hopefully function better. I pretend all day every day that I'm doing ok. I'm tired of it. I have tried the Duragesic patch but I had some problems with it and had to go off. That did help a little bit. I simply don't understand why I can't take a medication that will help me. Do you have any advice? Answer: Well, I hate to be the one to break the news, but Vicodin is a narcotic. And Vicodin can be very addicting. You need to talk to a rheumatologist. Rheumatoid arthritis in most cases should not be treated...
Generic Name: TRAMADOL/ACETAMINOPHEN - ORAL Pronounced: (TRAM-a-dol/a-SEET-a-MIN-oh-fen) Tramadol-Acetaminophen Oral Uses
This product is used to treat moderate to moderately
severe pain. It contains 2 medications: tramadol and acetaminophen. Tramadol is
similar to narcotic analgesics. It works in the brain to change how your body
feels and responds to pain. Acetaminophen is used to relieve pain, and it can
also reduce a fever.
How To Use Tramadol-Acetaminophen Oral
See also Warning section.
Take this medication by mouth as directed by your doctor,
usually every 4 to 6 hours as needed for pain relief. You may take this drug
with or without food. If you have nausea, it may help to take this drug with
food. Ask your doctor or pharmacist about other ways to decrease nausea (such
as lying down for 1 to 2 hours with as little head movement as
The dosage is based on your medical condition and response
to treatment. To redu...
Most everyone knows narcotic pain killers like morphine, Percocet, and Vicodin are powerful. Doctors prescribe them with caution because although they relieve pain, they also have some nasty side effects. Addiction being one of those effects. But sometimes physicians are too cautious not realizing that some people require 10 to 40 times the standard dose to get the same effect. Animal studies have confirmed what doctors see in the clinic -- there are some unique differences in patient responsiveness. Scientists have found that the wide variability in how people respond to these drugs might be genetic. And once they discovered this factor, they found more than one genetic trait that is involved. For example, some folks don't have the CYP2D6 enzyme needed to activate the drug. Without this enzyme, the drug isn't metabolized (broken down) and the patient gets no (or very minimal) pain relief. Another problem occurs when P-glycoprotein doesn't function properly. This is the protein that tra...
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