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Honestly I think you should tell your doctor. its a difficult situation for sure.  If its oxycontin you're taking, though, it can cause respiratory 'depression' or respiratory arrest - which can cause death. Opioids depress the activity of different parts of the central nervous system - one of the which is the respiratory functioning. For most people this is not a problem unless they combine the drug with another central nervous system depressant like alcohol but for others it is. Respiratory depression is the common serious side effect of the drug. You're being very smart not to take it before bed time   It's possible that you just need to take a lower dose at first. This site on oxycontin (http://pharma-help.com/oxycontin) states that its very important if you've never taken this drug before to start off in very low doses. It states,  for example, that you should never start off the drug using its 80 mg. tablet.  I think you should check with your doctor and hope for the best.