For some reason, Tramadol is an overlooked, misunderstood drug. Even some doctors are confused about some facts that seem to be little known. Most know that tramadol is used to treat pain and comes in both short acting and time released formulas. Various brand name drugs contain tramadol including: Ultracet, Ultram, Ultram ER, Ryzolt, and Rybix. Because these all contain tramadol, they are all worth considering even for the toughest to treat pain. But first, let's clear up some confusion about tramadol.
Is tramadol an opioid? So many people have been lead to believe that tramadol is not an opioid medication. In fact, tramadol is considered an opioid medication because it like morphine and hydrocodone bind to and activate the mu opioid receptor . This mechanism provides the pain relieving, the analgesic effect. And like all the other opioids, the regular use of tramadol can lead to physical dependency . Thus, when this exogenous source of opioids is withdrawn suddenly, a per...
Generic Name: TRAMADOL EXTENDED-RELEASE - ORAL Pronounced: (TRAH-muh-dall) Tramadol Oral Interactions
Drug interactions may change how your medications work or
increase your risk for serious side effects. This document does not contain all
possible drug interactions. Keep a list of all the products you use (including
prescription/nonprescription drugs and herbal products) and share it with your
doctor and pharmacist. Do not start, stop, or change the dosage of any
medicines without your doctor's approval.
Some products that may interact with this drug
certain pain medications (mixed narcotic agonist-antagonists
such as pentazocine, nalbuphine, butorphanol)
narcotic antagonists (such as naltrexone)
Avoid taking MAO inhibitors (isocarboxazid, linezolid,
methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline,
tranylcypromine) within 2 weeks before and during treatment with this
T he study called ACCORD (Action to Control Cardiovascular Risk in Diabetes) is back in the news. The study, which included 10,251 patients with type 2 diabetes mellitus and who were at especially high risk of cardiovascular events (such as heart attacks, stroke, or death from cardiovascular disease). The study should not be extrapolated to patients with type 2 diabetes "who are younger, whose diagnosis is more recent, or who have a lower risk of CVD than participants studied in the ACCORD trials. It is not known what effect more intensive therapy might have on CVD in younger people with type 2 diabetes or in patients with a lower risk of CVD than were studied in ACCORD" (per a NIH Q&A about the study).
I have previously written (several times!) about earlier results from the ACCORD trial, which surprised experts when it was announced that patients in the tight-glucose-control part of the study (aiming for A1C below 6.0) had more deaths than patients in the standard-glucose...
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