Generic Name: TRAMADOL EXTENDED-RELEASE - ORAL Pronounced: (TRAH-muh-dall) Tramadol Oral Interactions
Drug interactions may change how your medications work or
increase your risk for serious side effects. This document does not contain all
possible drug interactions. Keep a list of all the products you use (including
prescription/nonprescription drugs and herbal products) and share it with your
doctor and pharmacist. Do not start, stop, or change the dosage of any
medicines without your doctor's approval.
Some products that may interact with this drug
certain pain medications (mixed narcotic agonist-antagonists
such as pentazocine, nalbuphine, butorphanol)
narcotic antagonists (such as naltrexone)
Avoid taking MAO inhibitors (isocarboxazid, linezolid,
methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline,
tranylcypromine) within 2 weeks before and during treatment with this
There has been a lot of news lately about medication overuse headaches (MOH) that may be linked to those of us who have chronic headaches each month. Do you think taking a 50mg tablet of Tramadol daily (for fibromyalgia) could be enough to cause MOH? Peggy.
Some patients can take tramadol daily without getting into a medication overuse headache. For others, that 50mg a day could cause MOH. If the tramadol IS causing you MOH, it should be relieved when you take the tramadol.
This is a rock-and-a-hard-place problem for people who have both headache and pain issues. Sadly, there's no good solution for it.
Good luck, John Claude Krusz and Teri Robert
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T he study called ACCORD (Action to Control Cardiovascular Risk in Diabetes) is back in the news. The study, which included 10,251 patients with type 2 diabetes mellitus and who were at especially high risk of cardiovascular events (such as heart attacks, stroke, or death from cardiovascular disease). The study should not be extrapolated to patients with type 2 diabetes "who are younger, whose diagnosis is more recent, or who have a lower risk of CVD than participants studied in the ACCORD trials. It is not known what effect more intensive therapy might have on CVD in younger people with type 2 diabetes or in patients with a lower risk of CVD than were studied in ACCORD" (per a NIH Q&A about the study).
I have previously written (several times!) about earlier results from the ACCORD trial, which surprised experts when it was announced that patients in the tight-glucose-control part of the study (aiming for A1C below 6.0) had more deaths than patients in the standard-glucose...
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