A new study, presented at the 29th Annual Scientific Meeting of the American Pain Society in Baltimore earlier this month, gave doctors one more treatment option to consider for fibromyalgia patients . The study found that FM patients who did not have particularly good results from taking Lyrica alone experienced significantly reduced pain and greater overall improvement when taking Savella in addition to the Lyrica. Since Lyrica is effective for only about one third of FM patients, and since Lyrica and Savella have different mechanisms of action, the researchers wanted to see what happened when they were combined. Study Methods and Results In this study 173 patients were given just Lyrica and 179 were given Lyrica plus Savella for 11 weeks. The dosages used were 150 or 225 mg of Lyrica twice a day and 50 mg of Savella twice a day. By week 11, the pain scores of the Lyrica group dropped four points as measured by the Visual Analog Scale, while the pain scores of t...
Our readers ask some great questions about Migraine disease and other headache disorders here on HealthCentral's Migraine community. Nancy and I both answer questions in our community question and answer section . Dr. Krusz and I answer other questions in our Ask the Clinician column .
Some of the questions apply to many of our readers, and are great topics for discussion. So, every week, I bring you our Question of the Week. I hope you'll take a few minutes to look at these questions and the answers, then join us in discussion. One of the best things about online communities is the opportunity to share information and experiences.
This week's Question of the Week:
I have been on everything for Migraines and now my doctor want to put me on lyrica...?
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Migraine and Headache Specialists - What's So Special?
Patient Recommended Migraine and Headache Specialists
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Last week Lupin Pharmaceuticals, Inc. issued a press release announcing that it has received final FDA approval to market pregabalin, the generic version of Lyrica ® in the U.S.
Lyrica (pregabalin) was the first drug ever to be approved for the treatment of fibromyalgia . In addition to fibromyalgia, it has also been approved by the FDA for:
Treatment of neuropathic pain associated with diabetic peripheral neuropathy.
Treatment of post herpetic neuralgia.
Use an adjunctive therapy for adult patients with partial onset seizures.
Lupin's pregabalin capsules, to be available in 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg and 300 mg doses, are the AB-rated generic equivalent of Lyrica. An AB rating means that the generic drug has been studied and has demonstrated that it is bioequivalent to the original drug.
According to the FDA, "Bioequivalence of different formulations of the same drug substance involves equivalence with respect to the rate and ...
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