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According to study results presented Monday, May 1 at the American Academy of Neurology’s annual meeting, a significant number of fibromyalgia patients treated with Pfizer’s Lyrica (generic name pregabalin) experienced a 50 percent or more reduction in pain. They also reported significant improvements in overall health status and outcomes, including measures such as physical function and ability to perform everyday tasks. The 14-week placebo-controlled study included 745 patients with fibromyalgia who were randomized into four groups. One group received a placebo while the other three groups received 300mg, 450mg, or 600mg of Lyrica daily. Of those patients taking 600mg of Lyrica a day, 30 percent said their pain was cut in half or better; 27 percent of those taking 450mg a day and 24 percent of those taking 300mg also reported a similar level of pain relief. Of those taking the placebo, 15 percent reported pain reduction of 50 percent or better.&nb...
Our readers ask some great questions about Migraine disease and other headache disorders here on HealthCentral's Migraine community. Nancy and I both answer questions in our community question and answer section . Dr. Krusz and I answer other questions in our Ask the Clinician column .
Some of the questions apply to many of our readers, and are great topics for discussion. So, every week, I bring you our Question of the Week. I hope you'll take a few minutes to look at these questions and the answers, then join us in discussion. One of the best things about online communities is the opportunity to share information and experiences.
This week's Question of the Week:
I have been on everything for Migraines and now my doctor want to put me on lyrica...?
Join the discussion!
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Migraine and Headache Specialists - What's So Special?
Patient Recommended Migraine and Headache Specialists
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Last week Lupin Pharmaceuticals, Inc. issued a press release announcing that it has received final FDA approval to market pregabalin, the generic version of Lyrica ® in the U.S.
Lyrica (pregabalin) was the first drug ever to be approved for the treatment of fibromyalgia . In addition to fibromyalgia, it has also been approved by the FDA for:
Treatment of neuropathic pain associated with diabetic peripheral neuropathy.
Treatment of post herpetic neuralgia.
Use an adjunctive therapy for adult patients with partial onset seizures.
Lupin's pregabalin capsules, to be available in 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg and 300 mg doses, are the AB-rated generic equivalent of Lyrica. An AB rating means that the generic drug has been studied and has demonstrated that it is bioequivalent to the original drug.
According to the FDA, "Bioequivalence of different formulations of the same drug substance involves equivalence with respect to the rate and ...
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