A new study, presented at the 29th Annual Scientific Meeting of the American Pain Society in Baltimore earlier this month, gave doctors one more treatment option to consider for fibromyalgia patients . The study found that FM patients who did not have particularly good results from taking Lyrica alone experienced significantly reduced pain and greater overall improvement when taking Savella in addition to the Lyrica. Since Lyrica is effective for only about one third of FM patients, and since Lyrica and Savella have different mechanisms of action, the researchers wanted to see what happened when they were combined. Study Methods and Results In this study 173 patients were given just Lyrica and 179 were given Lyrica plus Savella for 11 weeks. The dosages used were 150 or 225 mg of Lyrica twice a day and 50 mg of Savella twice a day. By week 11, the pain scores of the Lyrica group dropped four points as measured by the Visual Analog Scale, while the pain scores of t...
Our readers ask some great questions about Migraine disease and other headache disorders here on HealthCentral's Migraine community. Nancy and I both answer questions in our community question and answer section . Dr. Krusz and I answer other questions in our Ask the Clinician column .
Some of the questions apply to many of our readers, and are great topics for discussion. So, every week, I bring you our Question of the Week. I hope you'll take a few minutes to look at these questions and the answers, then join us in discussion. One of the best things about online communities is the opportunity to share information and experiences.
This week's Question of the Week:
I have been on everything for Migraines and now my doctor want to put me on lyrica...?
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Two weeks ago I told you that the FDA approved a generic version of Lyrica ® (pregabalin) made by Lupin Limited, but I wasn't able to find out when it might actually be available on the market. Now I know why I couldn't find that information. Apparently Lupin was awaiting a court decision as to whether or not on Pfizer Inc.'s patents for Lyrica were valid.
That decision came down last Thursday, July 19, 2012. Judge Gregory M. Sleet of the U.S. District Court of Delaware upheld the validity of Pfizer's patents for Lyrica, giving them exclusive rights to the medication until December 30, 2018. In addition, Judge Sleet ordered the FDA to stop approving generic forms of pregabalin until Pfizer's patents expire.
The Story Behind the Decision
In 2009, Pfizer filed a lawsuit charging patent infringement against Israel's Teva Pharmaceutical Industries, India's Sun Pharmaceutical Industries, and U.S. firms Mylan and Watson Pharmaceuticals, who all sought FDA approval ...
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