According to study results presented Monday, May 1 at the American Academy of Neurology’s annual meeting, a significant number of fibromyalgia patients treated with Pfizer’s Lyrica (generic name pregabalin) experienced a 50 percent or more reduction in pain. They also reported significant improvements in overall health status and outcomes, including measures such as physical function and ability to perform everyday tasks. The 14-week placebo-controlled study included 745 patients with fibromyalgia who were randomized into four groups. One group received a placebo while the other three groups received 300mg, 450mg, or 600mg of Lyrica daily. Of those patients taking 600mg of Lyrica a day, 30 percent said their pain was cut in half or better; 27 percent of those taking 450mg a day and 24 percent of those taking 300mg also reported a similar level of pain relief. Of those taking the placebo, 15 percent reported pain reduction of 50 percent or better.&nb...
A new study, presented at the 29th Annual Scientific Meeting of the American Pain Society in Baltimore earlier this month, gave doctors one more treatment option to consider for fibromyalgia patients . The study found that FM patients who did not have particularly good results from taking Lyrica alone experienced significantly reduced pain and greater overall improvement when taking Savella in addition to the Lyrica. Since Lyrica is effective for only about one third of FM patients, and since Lyrica and Savella have different mechanisms of action, the researchers wanted to see what happened when they were combined. Study Methods and Results In this study 173 patients were given just Lyrica and 179 were given Lyrica plus Savella for 11 weeks. The dosages used were 150 or 225 mg of Lyrica twice a day and 50 mg of Savella twice a day. By week 11, the pain scores of the Lyrica group dropped four points as measured by the Visual Analog Scale, while the pain scores of t...
Our readers ask some great questions about Migraine disease and other headache disorders here on HealthCentral's Migraine community. Nancy and I both answer questions in our community question and answer section . Dr. Krusz and I answer other questions in our Ask the Clinician column .
Some of the questions apply to many of our readers, and are great topics for discussion. So, every week, I bring you our Question of the Week. I hope you'll take a few minutes to look at these questions and the answers, then join us in discussion. One of the best things about online communities is the opportunity to share information and experiences.
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I have been on everything for Migraines and now my doctor want to put me on lyrica...?
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