Yesterday the U.S. Food and Drug Administration announced that it is asking manufacturers of prescription combination products that contain acetaminophen to limit the amount of acetaminophen to no more than 325 mg (milligrams) in each tablet or capsule. Acetaminophen is probably best known by the brand name Tylenol. Outside the U.S., it is often called paracetamol and on prescriptions it may be labeled as APAP (For example, hydrocodone APAP). The drugs most affected by this action are opioid pain relievers that are combined with acetaminophen like codeine (Tylenol #3), hydrocodone (Vicodin, Lortab) and oxycodone (Percocet). “FDA is taking this action to make prescription combination pain medications containing acetaminophen safer for patients to use,” said Sandra Kweder, M.D., deputy director of the Office of New Drugs in FDA’s Center for Drug Evaluation and Research (CDER). “Overdose from prescription combination products containing acetaminop...
Generic Name: ACETAMINOPHEN/ANTIHISTAMINE - ORAL Chlorpheniramine-Acetaminophen Oral Interactions
If you are taking this medication under your doctor's
direction, your doctor or pharmacist may already be aware of any possible drug
interactions and may be monitoring you for them. Do not start, stop, or change
the dosage of any medicine before checking with your doctor or pharmacist
Before using this product, tell your doctor or pharmacist
of all prescription and nonprescription/herbal products you may use, especially
antihistamines applied to the skin (such as diphenhydramine
cream, ointment, spray)
"blood thinners" (such as warfarin)
MAO inhibitors (isocarboxazid, linezolid, methylene blue,
moclobemide, phenelzine, procarbazine, rasagiline, selegiline,
Tell your doctor or pharmacist if you are taking other
products that cause drowsiness, including alcohol, other antihist...
Alternative Names Tylenol # 3 overdose; Phenaphen with codeine overdose; Tylenol with codeine overdose Home Treatment Seek immediate medical help. This type of overdose can cause death. Do NOT make the person throw up unless told to do so by poison control or a health care professional. Before Calling Emergency Determine the following information: Patient's age, weight, and condition Name of the product (as well as the ingredients and strength, if known) Time it was swallowed Amount swallowed If the medication was prescribed for the patient Poison Control, or a local emergency number The National Poison Control Center (1-800-222-1222) can be called from anywhere in the United States. This national hotline number will let you talk to experts in poisoning. They will give you further instructions. This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It do...
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