FROM OUR EXPERTS
Like most of you, I take aspirin daily, 162.5mg (it used to be 325 until my stomach rebelled). Most cardiologists recommend aspirin for heart disease sufferers.
Aspirin works by interfering with the generation of thromboxane A2 (TXA2) which is needed for platelet aggregation (clotting). The COX-1 enzyme acts on arachidonic acid (AA) to produce endoperoxides that in turn produce TXA2. Aspirin interferes with the generation of TXA2 by irreversably acetylating the platelet COX-1 enzyme thereby blocking its access to AA. Because platelets are anucleate , they cannot generate additional COX-1. In the absence of TXA2, platelet aggregation does not occur. Got all that?! Most practitioners prescribe anywhere from 81mg to 325mg for heart patients. Studies such as CURE suggest 81mg is optimal. The ISIS-2 study puts the dose at 162mg (for recent heart attack sufferers) and, frankly, since aspirin is so cheap, many simply make the leap to "more must be better." Ahh, but there are downsi...
At first, you celebrated when your girlfriend got the amazing Internet job in Seattle; but that was before you got a fellowship to N.Y.U. Now, six months later, the two of you are experts at the ins and outs of cybersex, you've racked up enough frequent-flier miles to circle the globe, and your phone bills are through the roof. Welcome to the long-distance relationship, 21st century style. If this scenario sounds familiar, you're in good company. There are some very high-profile LDRs (long-distance relationships) out there. Just ask Bush's Britain-bound Gavin Rossdale how much he misses his L.A. woman, Gwen Stefani of No Doubt. Or Yalie Claire Danes, who's literally on the other side of the planet from her sweetie, Australian rocker Ben Lee. Even those of us who aren't dating rock stars know that our turbocharged ambitions and fast-paced careers are taking us, and our relationships, across the country and all over the world. Is an LDR For You? The most important fac...
I took a oxycodone 5mg and 15 min later was given a toradol shot. Is this safe? Amy.
There are no significant interactions between these two medications to make the combination unsafe.
That said, it doesn't mean they're safe for you. It depends on more than those two medications. It also depends on all other medications you're taking and any medical issues you may have. Hopefully, you remembered to tell the doctor who ordered the Toradol about the oxycodone, and he or she considered that before ordering the Toradol.
Good luck, John Claude Krusz and Teri Robert
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Dr. Krusz is a recognized expert in the fields of headache and Migraine treatment and pain treatment. Each week, he and Le...
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