FROM OUR EXPERTS
Generic Name: IBUPROFEN/OXYCODONE 400 MG/5 MG - ORAL Pronounced: (eye-byou-PRO-fen/ox-ee-KOH-doan) Ibuprofen-Oxycodone Oral Uses
This medication is used for the short-term treatment of
moderate to severe pain. It contains 2 pain relievers: oxycodone and ibuprofen.
Oxycodone is a narcotic pain reliever (opiate-type) that acts on certain parts
of the brain to relieve pain. Ibuprofen is a nonsteroidal anti-inflammatory
drug (NSAID) that works by blocking a certain natural substance in your body to
reduce pain and swelling.
How To Use Ibuprofen-Oxycodone Oral
Read the Medication Guide provided by your pharmacist
before you start using this product and each time you get a refill. If you have
any questions regarding the information, consult your doctor or
Take this medication by mouth with a full glass of water
(8 ounces or 240 milliliters) unless your doctor directs you otherwise. Do not
lie down for at least 10 minutes after ...
Like most of you, I take aspirin daily, 162.5mg (it used to be 325 until my stomach rebelled). Most cardiologists recommend aspirin for heart disease sufferers.
Aspirin works by interfering with the generation of thromboxane A2 (TXA2) which is needed for platelet aggregation (clotting). The COX-1 enzyme acts on arachidonic acid (AA) to produce endoperoxides that in turn produce TXA2. Aspirin interferes with the generation of TXA2 by irreversably acetylating the platelet COX-1 enzyme thereby blocking its access to AA. Because platelets are anucleate , they cannot generate additional COX-1. In the absence of TXA2, platelet aggregation does not occur. Got all that?! Most practitioners prescribe anywhere from 81mg to 325mg for heart patients. Studies such as CURE suggest 81mg is optimal. The ISIS-2 study puts the dose at 162mg (for recent heart attack sufferers) and, frankly, since aspirin is so cheap, many simply make the leap to "more must be better." Ahh, but there are downsi...
I took a oxycodone 5mg and 15 min later was given a toradol shot. Is this safe? Amy.
There are no significant interactions between these two medications to make the combination unsafe.
That said, it doesn't mean they're safe for you. It depends on more than those two medications. It also depends on all other medications you're taking and any medical issues you may have. Hopefully, you remembered to tell the doctor who ordered the Toradol about the oxycodone, and he or she considered that before ordering the Toradol.
Good luck, John Claude Krusz and Teri Robert
If you need help finding a Migraine and headache specialist, visit our listing of Patient Recommended Specialists .
About Ask the Clinician :
Dr. Krusz is a recognized expert in the fields of headache and Migraine treatment and pain treatment. Each week, he and Le...
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