Generic Name: OXYCODONE/ACETAMINOPHEN - ORAL Pronounced: (OX-i-KOE-done/a-SEET-a-MIN-oh-fen) Oxycodone-Acetaminophen Oral Uses
This combination medication is used to help relieve
moderate to severe pain. It contains a narcotic pain reliever (oxycodone) and a
non-narcotic pain reliever (acetaminophen). Oxycodone works in the brain to
change how your body feels and responds to pain. Acetaminophen can also reduce
How To Use Oxycodone-Acetaminophen Oral
See also Warning section.
Take this medication by mouth as directed by your doctor.
You may take this drug with or without food. If you have nausea, it may help to
take this drug with food. Ask your doctor or pharmacist about other ways to
decrease nausea (such as lying down for 1 to 2 hours with as little head
movement as possible).
If you are using a liquid form of this medication, use a
medication measuring device to carefully measure the prescribed dose. Do not
use a ho...
Voluntary recalls were issued for specific lots of two opioid pain relievers and one medication for tension headaches. The affected drugs include:
Endocet (oxycodone/acetaminophen), 10/325 mg
Hydrocodone/acetaminophen, 7.5/500 mg
Butalbital/acetaminophen/caffeine, 50/325/40 mg
Endocet (oxycodone/acetaminophen) Endo Pharmaceuticals issued the nationwide Endocet recall because a bottle from each of two lots was found to contain some 10/650 mg tablets, which is twice the dosage of acetaminophen on the label. Because of this, consumers may take more than the intended acetaminophen dose. Possible Dangers: Unintentional administration of tablets with increased acetaminophen content may result in liver toxicity, especially in patients on other acetaminophen containing medications, patients with liver dysfunction, or people who consume more than 3 alcoholic beverages a day. Lots: The two lots affected are Lot # 402415NV and Lot # 402426NV. They were distri...
It's not unusual for people living with chronic pain to also be dealing with some depression and/or anxiety . But if you're taking an opioid like oxycodone for the pain and also taking an herbal supplement containing St. John's Wort, you may unknowingly be reducing the effectiveness of your pain medication. A small study in Finland found that when St. John's Wort and oxycodone were taken together, the plasma concentration of oxycodone decreased by 50 percent and its half-life (the time it takes for half the drug to be elimitated from the body) was shortened by 27 percent. The reason for the significant decrease in oxycodone's effectiveness may lie in the fact that St. John’s wort is a well-known to induce CYP450 liver enzymes, which play an important role in the metabolism of many opioids. Although oxycodone was the only opioid tested, it would be logical to think that other opioids which are metabolized through the CYP450 pathways might be similarly...
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