Thursday, February 16, 2012

Saturday, July 05, 2008 Waleli asks

Q: Question about a safe dosage of NSAIDS

HI~I have lupus along with vasculitis and dysautonomia[msa]. I am on oxycontin for severe pain associated with the lupus and was wondering if it is safe to continue to take a doasage of
Ibuprophen at 800mg 2x a day or if I can go higher? I should also mention that I am on a maintenance dose of 5-10 mg prednisone every day as well.

Even with the oxycontin[20mg extended relief]I am still experiencing some pain and it is keeping me up at night.

Thank you for your help and input.

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Answers (1)
7/ 7/08 12:03pm

 Ibuprofen is certainly not a benign drug. High doses can increase the risk of stroke or heart attack and serious bleeding the stomach and intestines - you should generally as little as Ibuprofen as possible to achieve relief. Do not drink alcohol as it can increase the risk of stomach bleeding.

 

For more on side effects:

 

http://www.drugs.com/ibuprofen.html

 

Medicine.net states that when under care of a doctor your maximum dose of Ibuprofen is 3.2 grams a day. However there is a drug called Combunox which combines Ibuprofen and oxycodone (oxycontine). It has 400 mgs of ibuprofen and the maximum recommended dose is 4/day (1600) - thats exactly where you're at right now.  This suggests, unfortunately, that you should not go any higher and you should contact your physician to see about other remedies. Interestingly Combunox is only recommended for short-term use.

 

http://www.drugs.com/combunox.html

 

http://www.medicinenet.com/ibuprofen/article.htm

 

Good luck!

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