A couple of things, If the acetamenaphen is helping you better than the 5/500 would work better and if the hydrocodone is helping you better than 10/325 may be for you. everyone is different and medications react differently to different people. For me I prefer the 5/500 and taking 2 of those compaired to 2 10/325 so all depends on the problem for taking it and the person taking it.
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