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Hand-foot syndrome (HFS), or Palmar-Plantar Erythrodysesthesia (PPE), is a side effect of some types of chemotherapy and other medicines used to treat breast cancer. Hand-foot syndrome is a skin reaction that occurs when a small amount of the medication leaks out of capillaries (small blood vessels), usually on the palms of the hands and soles of the feet. When the medication leaks out of the capillaries, it can damage the surrounding tissues. Hand-foot syndrome can be painful and can affect your daily living.
Symptoms of hand-foot syndrome include:
tingling, burning, or itching sensation
redness (resembling a sunburn)
In severe cases of hand-foot syndrome you may have:
cracked, flaking, or peeling skin
blisters, ulcers, or sores appearing on your skin
difficulty walking or using your hands
The following breast cancer medications can cause hand-foot syndrome:
Xeloda (chemical name: capecitabine)
Adrucil (chemical name: 5-f...
Definition Alternative Names Causes of foot pain Information Question: What causes foot pain? Answer: Many things can cause foot pain . Wearing shoes that don't fit right is one of the most common reasons people (especially women) get foot problems such as calluses and bunions . With age, feet often grow wider. Also, being overweight can increase your chances of having foot problems or injuries. Go shopping for shoes in the afternoon when your feet are at their largest due to swelling . Heels on shoes shouldn't be higher than 1 inch. Shoes with a wide toe box can also lead to less problems to your feet. See also: Ankle pain Heel pain
Foot Injury If you suspect that you have broken or fractured bones in a toe or foot, call a doctor, who will probably order x-rays. Even if you can walk, you still might have a fracture. People are often able to walk even if a foot bone has been fractured, particularly if it is a chipped bone or a toe fracture. Over-the-Counter Pain Relievers Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat mild pain caused by muscle inflammation. Aspirin is the most common NSAID. Others include ibuprofen (Motrin, Advil, Nuprin, Rufen), ketoprofen (Actron, Orudis KT), naproxen (Aleve, Naprelan), and tolmetin (Tolectin). A gel containing ibuprofen can be applied to sore joints. Acetaminophen (Tylenol) is not an NSAID, and although it is a mild pain reliever, it will not reduce inflammation. It is important to note that high doses or long-term use of any NSAID can cause gastrointestinal disturbances with sometimes serious consequences, including dangerous bleeding. ...
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