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Saturday, March 28, 2009 Shelbie, Community Member, asks

Q: My wife was taking Hydroco/APAP 7.5-325 but the doctor changed her prescripion to Hydrocodone-APAP 7

My wife was taking Hydroco/APAP 7.5-350 (Norco) but her new doctor changed her

prescription to Hydrocodone-APAP 7.5-750. Which of the two is stronger? What is the


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Answers (3)
Street PHD, Community Member
4/ 1/09 11:04pm

the only difference is the tylenol amount.  basically they dont want her taking as many pills and increasing the tylenol amount reduces the suggested doses per day to not exceed over 4000 mg of tylenol. all in all there is no real difference of what is stronger.

Pain, Community Member
3/28/09 9:32pm

APAP = Tylenol


They both have the same amount of hydrocodone (7.5mg) but the new one has more tylenol in it (750mg vs. 325mg)


The second is a bit stronger.

Debra, Community Member
6/24/10 1:12pm

I would use the 7.5 325 less tylenol better on your liver..the 7.5 is the narcotic strenght and the 350 and 750 has amount of tylenol..doc just switched me to the lower dose cause norco is suppose to be liver friendly.

janice, Community Member
9/18/11 10:08am

Do they both have same amount of codine

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By Shelbie, Community Member— Last Modified: 09/17/14, First Published: 03/28/09