Darvon Compound-65 contains aspirin and caffeine. If you have an ulcer or a blood clotting problem, consult your doctor before taking this medication. Aspirin may irritate the stomach lining and could cause bleeding.
Because there is a possible association between aspirin and the severe neurological disorder known as Reye's syndrome, children and teenagers with chickenpox or flu should not take Darvon Compound-65 unless prescribed by a doctor.
Aspirin may cause asthma attacks. If you have had an asthma attack while taking aspirin, consult your doctor before you take Darvon Compound-65.
Possible food and drug interactions when taking this medication
The propoxyphene in these drugs slows down the central nervous system and intensifies the effects of alcohol. Heavy use of alcohol with this drug may cause overdose symptoms. Therefore, limit or avoid use of alcohol while you are taking this medication.
If these medications are taken with certain other drugs, the
effects of either could be increased, decreased, or altered. It is
especially important to check with your doctor before combining
them with the following:
Antiseizure medications such as Tegretol
Antidepressant drugs such as Elavil
Antihistamines such as Benadryl
Muscle relaxants such as Flexeril
Narcotic pain relievers such as Demerol
Sleep aids such as Halcion
Tranquilizers such as Xanax and Valium
Warfarin-like drugs such as Coumadin
The use of these drugs with propoxyphene can lead to potentially fatal overdose symptoms.
Severe neurologic disorders, including coma, have occurred with the use of propoxyphene in combination with Tegretol.
The use of anticoagulants (blood thinners such as Coumadin) in combination with Darvon Compound-65 may cause bleeding. If you are taking an anticoagulant, consult your doctor before taking this drug.
The use of aspirin with drugs for gout may alter the effects of the antigout medication. Consult your doctor before taking Darvon Compound-65.
Special information if you are pregnant or breastfeeding
Do not take these medications if you are pregnant or planning to become pregnant unless you are directed to do so by your doctor. Temporary drug dependence may occur in newborns when the mother has taken this drug consistently in the weeks before delivery. The use of Darvon Compound-65 (which contains aspirin) during pregnancy may cause problems in the developing baby or complications during delivery. Do not take it during the last 3 months of pregnancy. Darvocet-N does appear in breast milk. However, no adverse effects have been found in nursing infants.
