IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate or effective for you. Consult your healthcare professional before using this drug.
Pain Relief Adult Oral Interactions
See also Warning section.
If you are taking this medication under your doctor's direction, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.
(See also adult maximum daily dose information in Side Effects section.)
This drug should not be used with the following medications because very serious interactions may occur:
If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this product.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of:
- antiplatelet drugs (e.g., clopidogrel, ticlopidine)
- "blood thinners" (e.g., warfarin, enoxaparin, heparin)
- NSAIDs (nonsteroidal anti-inflammatory drugs such as ibuprofen, naproxen)
- corticosteroids (e.g., prednisone)
- oral bisphosphonates (e.g., alendronate)
- certain medications for gout (e.g., probenecid, sulfinpyrazone)
- drugs used for diabetes (e.g., glyburide)
- anti-seizure drugs (e.g., carbamazepine, phenytoin, valproic acid)
- high blood pressure drugs (including ACE inhibitors such as captopril, angiotensin II receptor antagonists such as losartan)
- SSRI antidepressants (e.g., fluoxetine, sertraline)
- "water pills" (diuretics such as furosemide, spironolactone)
Consult your doctor before using this product if you have recently received certain live vaccines (e.g., varicella vaccine, influenza intranasal vaccine).
Check all prescription and nonprescription medicine labels carefully since many contain pain relievers/fever reducers (acetaminophen, aspirin, or NSAIDs such as ibuprofen, celecoxib, naproxen) and if taken together with this product, may increase your risk for side effects. Low-dose aspirin, as prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually these dosages are 81-325 milligrams per day), should be continued. Consult your doctor or pharmacist for more details.
This drug may affect certain laboratory tests (e.g., certain urinary sugar tests). Make sure laboratory personnel and your doctors know you are taking this medication.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
Information last revised January 2011 Copyright(c) 2011 First DataBank, Inc.