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Alka-Seltzer Plus Cold/Cough Oral Precautions and Side Effects


IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate or effective for you. Consult your healthcare professional before using this drug.

Table of Contents

Generic Name: DEXTROMETHORPHAN/DECONGESTANT/ACETAMINOPHEN/ANTIHISTAMINE - ORAL

Alka-Seltzer Plus Cold/Cough Oral Precautions

Before taking this product, tell your doctor or pharmacist if you are allergic to any of its ingredients; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

If you have any of the following health problems, consult your doctor or pharmacist before using this medication:

  • breathing problems (such as asthma, emphysema)
  • diabetes
  • glaucoma
  • heart problems
  • high blood pressure
  • kidney problems
  • liver disease
  • seizures
  • stomach/intestinal problems (such as blockage, constipation, ulcers)
  • overactive thyroid (hyperthyroidism)
  • urination problems (such as trouble urinating due to enlarged prostate, urinary retention)

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Acetaminophen may cause liver damage. Daily use of alcohol and acetaminophen may increase your risk. Avoid alcoholic beverages.

Some brands of this product may contain sugar, alcohol, or aspartame. Caution is advised if you have diabetes, alcohol dependence, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about using this product safely.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Children may be more sensitive to the effects of this drug. In young children, antihistamines may cause agitation/excitement instead of drowsiness.

Older adults may be more sensitive to the effects of this drug, especially dizziness, drowsiness, and mental/mood changes.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This medication may pass into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Alka-Seltzer Plus Cold/Cough Oral Side Effects

Drowsiness, dizziness, blurred vision, upset stomach, nausea, or dry mouth/nose/throat may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • mental/mood changes (such as confusion, hallucinations)
  • trouble urinating

Tell your doctor immediately if any of these rare but serious side effects occur:

  • fast/irregular heartbeat
  • seizure

Taking more than the recommended dose of acetaminophen may cause serious (possibly fatal) liver disease. Seek immediate medical attention if you have any of the following symptoms of liver damage:



CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
Information last revised December 2011 Copyright(c) 2011 First DataBank, Inc.