Buproban Oral

Buproban Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

• certain x-ray dyes such as iomeprol
• sibutramine
• thioridazine

If you are currently using any of these medications, tell your doctor or pharmacist before starting bupropion.

Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) during treatment and for 2 weeks before and after treatment with this medication. In some cases a serious, possibly fatal, drug interaction may occur.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

• amantadine
• diabetes medications (e.g., glipizide, glyburide, insulin)
• HIV drugs (e.g., efavirenz, nelfinavir, ritonavir)
• levodopa
• regular use of sedatives (e.g., benzodiazepines such as lorazepam)
• stimulants (e.g., amphetamine, cocaine, "ecstasy," ephedrine)
• warfarin

Also tell your doctor if you are taking any drugs which are affected by certain liver enzymes such as antidepressants (e.g., desipramine, paroxetine, fluoxetine), antipsychotics (e.g., haloperidol), beta-blockers (e.g., metoprolol), antiarrhythmics (e.g., propafenone, flecainide), orphenadrine, thiotepa, cyclophosphamide, carbamazepine, phenobarbital, or phenytoin, among others.

Also report the use of drugs which might increase seizure risk (decrease seizure threshold) when combined with bupropion such as corticosteroids (e.g., prednisone), isoniazid (INH), phenothiazines (e.g., chlorpromazine), theophylline, or tricyclic antidepressants (e.g., amitriptyline) among others. Consult your doctor or pharmacist for details