If you do a search of the questions we receive on MyDepressionConnection you will find that the number one inquiry is about the topic of antidepressant medications. It is no wonder that this is such a popular topic as it is the most utilized treatment for depression. In fact, more Americans are using prescription drugs to treat their depression than talk therapy. A study published in the Archives of General Psychiatry, reported that in 2005 approximately 10% of Americans or 27 million people were taking antidepressants. This rate was double the amount from 1996. Yet the percentage of antidepressant users who also received psychotherapy plummeted from 31.5% to less than 20%. In addition, a significant majority of patients (80%) are being prescribed antidepressants from doctors other than psychiatrists. The growing popularity of using prescription medication to treat depression leaves many questions. How did this trend happen? How are doctors and patients making this decision to use medication as the primary treatment for depression and in some cases the only treatment? In this post we are going to take a look at research to find our answers.
What is causing this dramatic increase in antidepressant usage?
One would hope that more people are being prescribed antidepressants because there are better diagnostic procedures to identify depression early on. Another optimistic view is that there is less stigma associated with having a mood disorder and patients are more willing to consider treatment. Yet these reasons probably play only a very small part in this growing trend. Here are some of the more plausible causes for the great increase in antidepressant use in the past decade:
• Pharmaceutical Advertising
This huge increase in the number of people taking antidepressants comes as no surprise when you understand how much time and money is invested in pharmaceutical advertising. In 1997 the US Food and Drug Administration released new guidelines which allowed for direct-to-consumer advertising. This is why you see all those antidepressant commercials on TV. Do these ads have any impact on patients and consumers? They sure do. According to a report published in The American Journal of Medicine a 2002 FDA survey found that 43% of respondents reacted to a drug advertisement by looking for more information about that drug. We are now, more than ever before, making specific medication requests from our doctors. And much of this is based upon advertising.
Here are some sobering statistics to bear in mind. This same report in The American Journal of Medicine states that: “Between 1996 and 2003, there was a 400% increase in spending on direct-to-consumer advertising from 791 million to $3.2 billion. In addition, a 2008 a study found a huge discrepancy between pharma reports of marketing expenditures and what independent analysis has found. The study authors found that pharmaceutical companies spend almost twice as much on promotion as they do on research and development. You can read the details of this study, “The Cost of Pushing Pills: A New Estimate of Pharmaceutical Promotion Expenditures in the United States" in the January 3, 2008 issue of PLoS Medicine, an online journal published by the Public Library of Science.



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Although I'm not sure what, if anything, should be done about it, I find alarming the fact that so many people who have not met the diagnostic criteria for depression or anxiety are still being prescribed antidepressants. Do doctors just feel pressured by patients, who in turn have been pressured by pharmaceutical companies who ambitiously advertise across a wide range of media? I took my first antidepressant (Tofranil) in 1974 or 75 and I was not aware of anyone else taking this class of meds at the time. Not long after, I remember it was scandalous when a neighbor of my aunt let her 5 yr old be put on Valium for a nervous condition. I know a friend recently who asked that her mother (who was in a nursing center) be put on antidepressants because she was crabby and hard to get along with. The doctor complied immediately. I know for a fact that her mother had always been hard to get along with, only now the daughter was in a position to commandeer her mother's medical care. Is that right?
Yes....yes and no to your questions.
This absolutely is happening. What I personally find alarming are the number of members who say they had done okay on a particular antidepressant and then the doctor wants to switch them to one of the new ones which are more costly and there is no generic version. Why is this happening? well....
As I did the research for this article I became more and more jaded.
Medication can be a life saver for so many. But...there is just something wrong with this whole process and nobody bats an eyelash anymore. I don't think people know.
Depression is being treated like the common cold...here take two of these and don't call me in the morning. Look at how many members ask medication questions. They aren't asking their doctor. Why? Because patients are not being talked to anymore...they are in and out. It is pretty much becoming a revolving door prescription mill.
I could go on...but this is making me feel depressed. So many people need help and they are not getting it. It is a crime.
I go to my psychiatrist today and I feel afraid to tell him the truth -- that when he put me back on 15mg of Zyprexa for a month, I actually only took 7.5mg for 9 days. The side effects were so horrendous I just couldn't take it any more -- literally! But the experience was good in that it made me really, really grateful for the meds I take that DON'T have side effects...or they have positive side effects like giving me more time awake and more energy.
I'm not sure why I don't want to tell him the truth; it's like I'm "disobeying" when in fact it is more like "informed action" that I took. And it is my life, my body, my money. Just one month of Zyprexa is $1,192. Of course, my insurance pays for most of that, but isn't that horrible?
Hey Donna
Just checking up on you...so what happened with your doctor?
Donna,
Please don't be afraid to tell your doctor about the side effects. You pay him! It is his job and duty as a physician to give you the very best care. I had a great doctor in Florida and now I have a not so good one in Illinois thay is constantly trying to get me to switch to more expensive medications. One went from $4 a month to $78. The medication caused me to turn bright red and my face to swell! And I don't get a refund from the pharmacy if a medication doesn't work. I put my foot down and insisted he switch me back to what I was taking before.
even the very best of doctors can't possibly know everything about each drug, much less how it is going to affect every individual. You must take charge and let him or her know when something is not working. When you do, you put your doctor in a better position to help you.
If you hesitate to say something because he or she might be busy, tell the recptionist/nurse that you will need 10-15 minutes to discuss some thing with the doctor. Then write down exactly what side effects you are having and what your concerns are and bring that into the office with you so you don't forget to mention something that could be vital information. Make sure you document the tine you took the medication, what you eating, and what other medications (even over the counter medications) you had taken.
Your doctor will have much more respect for you because you have taken the time to prepare him for a discussion and that you have solid, exact information he can refer to. Make notes of anything he tells you in the office and rephrase his words back to him to make sure you are both on thr same page.
Doctors, like all humans want to be successful at what they are doing. Letting him know what is or isn't working gives him more opportunity to help you and be successful.
Before I had to make a decision about crossing that boundary between truth and a lie, my doctor said, "I think this will work for you to just go back to the Zyprexa once every 6 months for a week or two till you get balanced again, don't you? And this is what I had already done. We didn't discuss halving the dose, which I had done on my own, so I didn't have to make the truth/lie decision that I dreaded.
He also suggested that I take a look at a new med that just came out toward the end of last year: Latuda. I was not familiar with it. He said the side effect profile is a little different -- more risks as far as raising lipid levels, but the advantage of decreasing the appetite. More risk of stomach upset, which I am already experiencing some on the Saphris, but a probable end to the constipation that has plagued me for over a year now. The two beneficial side effects are something I feel I might go for, but I would have to balance that against the fact that I am stable right now.
However, with continuing the Saphris, my sleep will doubtless continue to be poor (I awaken between 2 and 3am every morning and never go back to sleep.) That is a risk with the Latuda, too, but 23% of people on it slept better. There is some appetite increase with the Saphris, but I have managed to only gain about 4 lbs and it's not nearly the headache it had been on Zyprexa. And if the decrease of appetite on Latuda helped me to lose weight, it would counterbalance the lipid problem -- my PCP says if I lost weight I could likely get off of the high blood pressure and GERD meds and my cholesterol would probably decrease.
It is something to think about. Why mess with something that is working okay? I guess the grass is always greener on the other side.
Thank you, Suzie. Your suggestions sound great!