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"Will my Antidepressants Make me Gain Weight?" (Part One)

By Merely Me Monday, February 02, 2009

The answer to this question is that they just might, especially if you are taking a certain type of antidepressant. 

 

Of course there is a lot more to the story.  People gain and lose weight for a variety of reasons.  Being depressed in itself can cause great fluctuations in weight.  I know for me, I have had the experience of both gaining and losing weight while depressed.  When I am depressed and feel anxious I tend to lose weight.  When I am chronically mildly depressed over a long period of time, I tend to engage in mindless eating and gain weight. And likewise when I am feeling better and coming out of a depression, I eat more.  When I feel happy I tend to enjoy food more.  Everyone is different in how their weight will fluctuate with their mood.

 

One hypothesis for why some of us gain weight when we are taking antidepressants is that as we begin to feel better and rediscover pleasure, we like to eat more.  Some people, like me, eat more when we feel happier.

 

There could also be a medical reason for weight gain during depression.  An underactive thyroid problem can cause both depression and weight gain. An underactive thyroid can greatly change your energy level for the worse. The person who suffers from an underactive thyroid feels great fatigue, feels cold, has diminished concentration and memory, and suffers from weight gain. So if you are feeling tired, depressed, and gaining weight, it might be wise to go see your doctor to check out your thyroid.

 

But is there a connection between the use of some antidepressants and weight gain? 

 

Many antidepressant users and medical experts would say yes.

 

How many people are gaining weight on their antidepressants?  In an article entitled, "Fat Pharms:  Antidepressants and Weight Gain"   the author estimates that for up to 25% of the people who take anti-depressants will have a weight gain of ten pounds or more.  Add to this  Psychiatrist Daniel-Hall's prediction that: " Recent research has shown that people who gain weight within about the first week of starting antidepressant treatment are more likely to have significant weight gain from the medication over an extended period of time. "   So it seems if you start off gaining right away while on an antidepressant, this does not bode well for maintaining your weight in the long term. 

 

Which brings us to what you really want to know and that is:

 

"Which antidepressants are more likely to cause weight gain?

 

Predominantly the medical literature is in agreement that Paxil can cause you the most weight gain.  Of course it greatly depends on the individual but individuals report weight gain ranging from 20-50 pounds.  According to Janet Kinosian, in her article entitled, "Antidepressants & Weight Gain, she reports that Paxil, Zoloft, Remeron, and Luxox cause the most weight gain     

2/ 2/09 6:05pm

I am like you in that, feeling better seems to make food more attractive and thus needing more vigilance.Though chocolate is pretty good anytime.

Never noticed an immediate correlation between any antidepressants and weight, other than that.

I did use a small dose, 25mg., of amitriptyline (Elavil) for a very long time, not at an antidepressant dose, but as an aid to sleep, it stopped me from waking up 15 times a night.

2/ 3/09 12:55am

The spelling of Tofranil needs to be corrected.  I took Tofranil (Imipramine) for 20 years and yes it is still used.  At one time it was the golden standard.  It does promote weight gain, as do the others mentioned in the article, but with proper exercise the weight gain was manageable.  Remeron (Mirtazapine) similarly promotes weight gain.

Wink

2/ 4/09 5:41pm

Thank you Patience!

 

With my Multiple Sclerosis I am finding myself reversing letters when I write words.  I need all the help I can get!  So thank you for pointing out my spelling error...I will fix that now.  Smile

 

And thank you too for sharing your experience.  I will write part two of this series next week so stay tuned!

Anonymous
Anonymous
8/ 5/09 2:54pm

I took imipramine for 15 years and have been off of it for about 2 months and I am gaining weight at an alarming rate.  I am trying to pinpoint what is making me gain the weight and I thought maybe it was getting "off " an anti-depressant but everything I am reading states getting "on" an anti-depressant makes you gain the weight.  The only other thing that is new with me is I started taking Vitamin B12 shots 4 months ago but I can't find anywhere that taking B12 shots would make me gain either.  I AM MISERABLE!!  Any comments or suggestions?

Anonymous
Debbie Foti
9/19/09 8:59am

I would love to know if this is true.  I took Sertraline for approx 1 1 /2 years and have always had to be weight concious but since I stopped I have gain approx 15 lbs

I have tried to join Jenny Craig I have done appetite suppresents and had absoulutely no luck in losing the weight I am actually gaining.  So I am thinkin about going back on the anti depressants.  WHat should I do? 

Anonymous
Anonymous
1/17/10 2:31pm

I also am gaining weight after quitting my antidepressant; at an alarming rate.  I workout 5-6 days per week.  My weight has been consistent my entire life.  Not to say that occasionally I would gain a few pounds, but after watching my diet for a couple of weeks and continuing to exercise I would lose these few pounds.  THIS IS NOT happening anymore.  I've been off my AD for 3 months and have gained 12 pounds.  I've been running a lot more at the Health Club and it still won't come off; in fact my weight seems to be continuing to increase.   Have you had any luck?

2/19/11 3:17pm

Hi. After stopping Luvox and losing 14 of 21 punds gained on it, I started Sertraline. I gaied the 14 ppounds back plus an additional 5. I stopped on Dec 2 2010. It's now Feb 19 2011. I haven't lost anything despite running, weights and a healthy diet. I actually gained weight after stopping like you did. Can you please update how you are doing. I really need to know what to expect.

2/19/11 3:59pm

Any update on losing weight?

Anonymous
Anonymous
2/ 3/09 4:54pm

this makes me wonder if existing weight should be taken into account when prescribing a drug.  For some, weight gain might be beneficial, and for those for whom weight is an exacerbation of depression,  a drug that is known to cause weight gain would seem a terrible idea.  It certainly would be something the patient should be aware of prior to treatment I think.

2/ 3/09 11:41pm

When my doctor had me on a low dose of the Cymbalta I gained about 45 pounds in one year and have alot of panic attacks. Have a new Doc and she uped me to 60mg Cymbalta and 1mg Adavan. on the third day of this I was going crazy I could not sit still. I could not sleep and I was so wired up I giot very scared. I called and she said drop it back down to the 20mg. I'm not sure about the adavan because I have dry mouth and it makes me really dizzt (I though it was supposed to relax me, so I could sleep), but again I'm up all night. I go back to see her next week. I don't know what to do. I feel like crap ! and she said, Oh ! by your next visit you will feel so much better. OK I'm not feeling it.............................I'm throwing up, feel weak, dizzy, tired, nervious..............I don't want to leave the house. I feel so bad.........A rally bad taste in my mouth I can't get rid of............What the heck is going on?

2/ 5/09 2:39am

I've been takin Sertraline for about a year now and my weight has stayed about the same. I'm still trying to lose the same stone for about ten years now, the only difference is now that I dont worry as much. If I fancy those chocolates, I have them because they taste so good at the time and the guilt is not as bad as it used to be.

Anonymous
why
6/17/09 2:06pm

I've been taking sertraline and buspirone for about 6 months now. I have gained about 25 pounds and it's making me more depressed now that I feel like I'm fat.  I was feeling fine until I could not pull my pants up over my hips, and the ones I could pull up, I couldn't button or zip them. I have been tapering off of them now for the past month and a half. I am determined to lose this weight that has been added since starting these meds.

6/18/09 2:57am

Hi why.

 

I know what you mean. It' so annoying when the medicine your taking to feel better is actually making you feel bad about something else.

 

I cant completely blame the medication though, because I'm actually enjoying my food and loving cooking but what I do now is try to eat smaller portions and take regular excercise and also understand that my figure is not going to be the same as when I was twenty. Its a constant battle with me but now I eat and exercise for the way it makes me feel rather than on how it makes me look. ( well more so than how it makes me look.)

 

The medication I take definately helps me so I'm going to stick with it because my depression and anxiety is also a constant battle for me and they give me a little support.

 

I hope this helps a little  and good luck with the weight loss.  You sound very determined.Smile

Anonymous
why
6/18/09 10:30am

I feel better when I take my meds, except for the fact that I do believe that they are the reason for the weight gain.  I work out 5 days a week and have been doing so for a while now. I have had a membership to a gym for the past 4 years. I just recently started going more often due to the fact that I want to lose these extra pounds. I've been o.k. while trying to taper off the meds, although I get headaches and moody. I want to take my meds, but I don't.  I think I'm going to schedule an appointment with my doc. to see if there is any other meds. that might help me and with the weight part. I'm still young and want to have my figure back!

6/18/09 11:24am

Hi why. I think that's a good idea to speak to a professional. Thanks for getting back to me and could you let me know how you get on.

Anonymous
why
6/19/09 10:28am

Your welcome. I'm going to schedule an appointment with my doc. today for next week sometime. I'm happy to say that I've lost 1lb. in 2 weeks. I hope I can lose at least 10lbs. My trainer at the gym (Ladies Premier Fitness) says that she wants to help me lose at least 12 lbs. I was 98lbs. after stopping breastfeeding my second child. I started taking the meds and started packing on the weight----25lbs.  I didn't mind gaining a little weight because 98lbs. is too small, but the weight gain just wouldn't stop! So I'm not sure what you were asking about how I get on. What exactly were you asking me? and I'll let you know. Thanks.

6/19/09 12:21pm

Hi there. I meant could you let me know if you manange to lose the weight that you put on and how you manange to do it . I'm still trying to lose the ten pounds that I put on since my last child. Smile

Anonymous
why
6/25/09 2:58pm

I will let you know. Right now I'm watching(well trying to watch)what I eat, going to the gym 3-5 days a wk. and using the steam room while I'm there, and drinking plenty of water. I went to my Doc.on Monday and he told me that the meds did not cause me to gain weight, it was me being depressed that made me gain weight. Well I was depressed  a while before I decided to go to the Doc. and had not gained weight until I started taking the meds.--coincedence--I think so. Anyway the doc. wants me to continue taking my meds and referred me to a psychiatrist. Hopefully that will help with how I feel.

Anonymous
Mimi Lindauer
2/ 5/09 9:11am

Abilify is another promoted heavily RX and it does cause weight gain, also, so do believe the Doctors when they say differently.

Remember, they get to earn more money by using the folks that need help, as research subjects.

M

Anonymous
Mimi Lindauer
2/ 5/09 9:15am

My humor is soo "off the wall". Honestly, I mean, do NOT believe that anti-depressants

are not huge weight gainers!!!!

Mimi

Anonymous
Sandy
2/ 5/09 9:15am

Kiss  I  would  like  to  add  to  this  subject!  My  grandaughter  is  taking  abilify,  and  she  has  gained  at  least  30lbs.  over  at  least  6  months.  I  am  going  to  talk  with  her  doctor  about  this  problem.  thanks,  sandy

Anonymous
debbie
2/ 5/09 9:28am

I have been on effexor er 75mg for 1 1/2 years now.At the beginning I lost about 20 something pounds in approx 8 months. I really didn't do any thing different, but now I have gained 20 pounds back, and all in the stomach area. To me thats even more depressing gaining all that weight, after you got yourself in a small size clothing.  I'm almost 50, and @ the weight loss time, went out and bought myself a bikini, which looked great, but now, I wouldn't be caught dead in one. Does anyone have advice for me to get the weight down again, to make myself feel better about me. 

2/ 5/09 10:19am

I was taking it for fibromyalgia and gained weight steadily, despite eating healthy and doing what exercise I can in the winter.

I have been taken off of it now, and put on trazadone (desryl) for sleep issues. The Elavil did help me sleep better and took the edge off the pain from the fibro. I have been told it may not be as effective as the Elavil but I am not up for gaining anymore weight.

I am peri-menopausal as well, and that in itself causes weight gain.

Thank you for this series.

2/ 5/09 3:05pm

Thanks for writing the article.  I'd appreciate it if you'd specificially address Effexor XR in Part 2.  I have been on this med for 10+ years and have gained a lot of weight - more than 30 lbs.  There could be many factors but I have always thought the medication is one.

Anonymous
Anonymous
2/ 9/09 10:59am

I would also like to Effexor XR covered. I've been on it for 4 years (375mg) and gained 60 pounds. I look like someone who eats at least a pint of Ben & Jerry's every night and maybe for breakfast too but I don't. I eat right. And there's nothing I can do about it. When I was just on Zoloft, I gained weight but I could at least diet and take it off. NO DIET WORKS WITH EFFEXOR.

 

My anxiety and PTSD are under control with Effexor but actual depression had gotten worse from being so fat that I don't want to go outside, I don't want to get together with old friends, I think my relationship with my husband has suffered greatly too since I'm not attractive to him anymore as an obese woman.

 

Google Effexor and you'll see nightmare stories of getting off Effexor, so I feel stuck on this medication and with my body. I was a fat child who worked hard to take it off in my 20s and built my self-esteem. Now I'm reliving life as a fat person, compounding how bad I feel.

 

Most importantly, for those of us that are stuck on meds like Effexor, please cover what, if any, techniques have worked for losing weight because I have tried cutting calories, exercising, etc. and none have worked for me.

3/21/09 3:09am

I have been on it for several years and gained almost 50 pounds.  I find I am hungry all the time and can eat *a lot*, which was not normal for me before I went on it.

Anonymous
Anonymous
5/12/09 7:37pm

well i gained weight on effexor (also in stomach). I think honestly the best thing to do is go off it and try prozac (was able to  all the weight on prozac)

 

 

Anonymous
JSR
6/25/09 8:44pm

I've been on Effexor for about 8 years and have been continuously gaining weight on it despite the fact that my eating and excercise habits have been stable. I am now about 60lbs overweight and prediabetic. I've been working out 3 - 4 times a week since I learned I was prediabetic (about six months ago) and watching what I eat closely. Still I have not been able to lose weight (although my clothes are marginally looser). I've tried to transition to Welbutrin twice, which has no weight gain side effects. But adding insult to injury, it turns out I am allergic to Welbutrin in both its branded and generic forms (after two weeks on it I get a horrible, insanity-inducing rash).

 

This situation is beyond frustrating and almost as depressing as depression itself. I know I can never truly go off meds (I tried that once and almost wound up in a hospital). My depression is genetic (it runs rampant in my family) and therapy alone does not cure it. I just wish there was an alternative treatment that was effective without ruining other aspects of my life. I am willing to try transitioning to other meds that might have less severe side effects in this regard. I'd be interested in hearing from others who have been on other meds besides Effexor and if they've had better luck losing weight with the alternatives.

6/25/09 9:00pm

I went off effexor and feel better.  Although, the reason I quit taking it mainly was because it quit working for me, and I was getting depressed to the point of suicidal.  I, too, have a family history of depression but at the moment I am doing good without meds.  I am researching other meds, and think I will try SamE and see how it works for me.  I am also trying to find a new doc that knows more about treating depression that's genetic (my doc has been terrible and difficult to contact as well).  That's has been another saga in frustration!

2/26/10 12:06pm

I FEEL YOUR PAIN.  I GAINED 35LBS ON THIS NIGHTMARE DRUG AS WELL.  LIKE YOU I EAT RIGHT AND WORK OUT HARD 4-5 TIMES A WEEK AND STILL PUT ON THE WEIGHT - MAINLY MY MIDSECTION AND HIPS.  THERE IS HOPE. FOR ME THE WITHDRAWALS WERE NOT BAD.  I WAS ON 75MG A DAY AND I SIMPLY OPENED UP THE CAPSULE AND LOWERED MY GRANUAL INTAKE SLOWLY.  IF YOU DO THIS THEN YOU WILL BE FINE!  IT WEENED MYSELF FOR 2MO AND SLOWLY GOT OFF IT.  I SWITCHED TO AN ALL NATUARAL SUPPLEMENT FROM SWANSON'S. IT IS 5-HTP. THIS IS A NATURAL AMINO ACID SUPPLEMENT WITH ZERO SIDE EFFECTS.  SO FAR - NO PANIC ATTACKS AND I AM EFFEOR XR FREE.  GOOD LUCK!!

Anonymous
Joeygirl
2/ 5/09 3:54pm

Since I have been on Paxil for over 8 years my weight has been going up, and for a person who always had low blood pressure and blood sugar, both have gone up.  what I need is a paxil replacement without the side effects of weight gain....any thoughts?

Anonymous
joyce
9/25/09 1:07am

try paxil cr, because it is released gradually you don't experience the drop in sugar that makes you crave carbs...worked for me.

Kate, Editor
2/ 5/09 4:51pm

I gained 30 pounds on Effexor! It was a nightmare. On the other hand, it was the best antidepressant I've been on. After 7 years on Effexor, I just gave it up. It's not that it wasn't making me feel better - it was - but there were so many terrible side effects in addition to the weight gain, such as out of control sweating, getting up to pee a minimum of 4 times a night, etc.

2/ 5/09 5:44pm

I was on mirtazapine (Remeron, Zispin) for about 6 weeks and out on a considerable amount of weight.  It also wasn't very effective, and gave me restless legs, so I came off.  It has taken effort to get back to my pre-mirtazapine weight.  My tricyclics do not appear to increase my weight.

 

A big problem I had years ago was that I was put on danazol for endometriosis.  This resulted in a gain of about 30lb in a short period of time.  Even when I stopped, that never came off!

Anonymous
Tiffani
2/ 5/09 11:36pm

I am not sure that I gained an extra 20 lbs due to changing my antidepressant  but I have no other explanation for it. I started on Celexa about 5 months ago and my eating and exercise habits never changed and I am 34 so my metabolism has not stopped yet, but I gained quite a bit of weight. I cant fit into many of my jeans! I talked to my doc and he said he didnt think that it was because of the med. But it would be nice to know if maybe anyone else has this problem! Thanks

Anonymous
justme76
10/21/09 4:13pm

I am also on Celexa with the same problem. I was on zoloft for 10+ years before I started Celexa. Both of which put weight on me. Everytime I have ever stopped taking the medication I was able to lose all the weight in a few months. But then my depression and anxiety comes back and I have to take them again. My doctor did tell me that most anti depressants will have that side effect. Kind of a catch 22...either im skinny and depressed with anxiety attacks, or im miserable being fat with more control of my depression. I think its funny how most people on here say the same thing, they were fine till they took the meds, and their docs say its not the meds. The docs should come to this site and talk to these women and then tell us its not the meds!!

 

 

 

Anonymous
Jackie
11/13/09 10:57pm

My Wellbrutrin wasn't working so the doctor added 20mg of Celexa acouple months ago. I gained 16 lbs and have never had a problem with weight before then. When questioned her, she replied it was the Celexa and switched me to Lexapro. I've only been on it for acouple of weeks so can't really say yet.

Hope this helped!    

Anonymous
Joslyn
11/11/10 12:45pm

I went on Celexa over a year ago and began to gain weight right away. About 40 lbs in 6 months.  Before being on it I was very anxious and skinny, it took away my anxiety wonderfully but I could not believe the weight gain!! Then on top of that I became pregnant, and gained nearly an additional 60 lbs.  I do not believe i would have gained that much if I had not been on Celexa, especially as the first trimester I barely ate and threw up alot.  So that is a total of 100 lbs!! I had no appetite after giving birth and lost abotu 30 lbs right away but that has steadily come back on as I believe the Celexa causes a slow weight gain unless you practically starve yourself!  Now Ive switched to Wellbutrin in the past few weeks, so far I seem to possibly be able to lose weight as Ive lost about 3 lbs...so who knows??  It makes me more anxious, but that seems to be going away slowly.  Doctors often say that Celexa is weight neutral, its NOT!!!   I think if you are prone to easy weight gain you will most definitely gain weight on an SSRI. 

11/11/10 9:30pm

I gained 96 lbs from the meds -- you've got me beat!  Isn't it miserable?  I can be skinny and psychotic/depressed, or I can be fat and unhealthy physically as well as have a poor body image...but sane.

Anonymous
Joslyn
11/12/10 11:23am

Oh I know!! No one seems to understand that I can barely lose a lb.  Since I started on Celexa, I gained weight in the first week!  It was 2lbs up and one lb down as I struggled to keep it under control.  Now Im on wellbutrin, I havent seen much of a difference yet but I really hope it works.  I eat a normal diet, which maybe I should be super dieting, but since that doesnt yield results the way it would have before medication its too depressing to try.  My husband seems to think that I just havent decided I want to lose weight yet, and when I do the weight will come off...  maybe if I exercised very intensely it would, but I have a young toddler and I guess I am in denial that I have to work 2 to 3x harder than the normal person to lose weight (IF I can lose weight...which is a big IF).  I am not sedentary and walk everywhere I go.  When your weight gain was caused by a medication and youve been skinny your whole life, its a totally different sense of frustration.  I feel like Im not in control of my body so its difficult to get motivated.  Changing diet and increasing exercise used to result in a loss of 5 lbs per week or two.  Now Im just sooo lucky if I see a 2 lb difference and if I relax even one day that weight packs on plus an extra lb.    I want to know if this medication can literally destroy your metabolism or if people are able to lose weight after coming off?   I have always had thyroid problems too and I know this adds to the difficulty and possibly made me more susceptible to the weight gain side effect in the beginning.

11/12/10 1:37pm

I went from 93 lbs to 186 lbs -- exactly doubled my weight.  And I'm only 5'2".  I have thyroid problems too.  I wish I knew exactly what the mechanism is that causes so much weight gain from Zyprexa (that's the one that piled it on me).  Does it lower my metabolism?  Does my brain not know when my stomach is full?  I am ravenously hungry 24x7.  I bought a treadmill that I use 4+ times a week.  Occasionally I walk outside for a bit.  But I don't lose even when I am desperate to lose and really try.  I hate it.  But Zyprexa is the only med that works for me.  I have to take it.   Really, you know, life IS better WITH it mentally.  But I hate the probability of getting metabolic syndrome or diabetes.  And my family has a long history of diabetes.

Anonymous
Joslyn
11/12/10 3:27pm

Yes I want that answer too.  I went searching and found an interesting (yet depressing!!) article here: http://ezinearticles.com/?Antidepressants-and-Weight-Gain&id=175369  Im horrified to see that Wellbutrin can either cause extreme weight loss or extreme weight gain!!  Anyone who has gained weight on wellbutrin??  To the people making these drugs:  PLEASE try to find a solution to the weight gain issue!!!  To Donna, I guess we have no choice but to remain on a drug that keeps us healthy.  I have tried to come off SSRI's before, Im ok for awhile but then I become anxious again, and for my daughters sake I need to remain happy, even if Im not physically healthy(!?!)

Anonymous
Anonymous
2/ 6/09 6:07pm

One thing I've learned is if you need to be on antidepressants, by all means take them.  It is so important to get the help you need!  Since I have been off my meds, I've lost 45 pounds (without exercise!) so I know there is a correlation. But if I needed to be back on meds, I wouldn't worry about the weight gain until later.  Most doctors are aware of which meds cause more weight gain.  If it's an issue, discuss it with them.  They're there to help you!

Anonymous
Stephany, soulful sepulcher
2/ 6/09 11:41pm

I was diagnosed with CFS in 1989 and the doctor offered me something I never heard of: Prozac. He told me it would "lift my spirits and it's a weight loss promotor". I declined and took vitamins. That's when my youngest was 1 yrs. old. In 2003, my PCP offered me Prozac again, for stress and anxiety. It wound me up so badly I lost weight and my mind! The drug I've been on the longest is Xanax (and am currently removing it slowly) and I often wondered that being on it a decade changed my metabolism. Weight became increasingly easy to gain and hard to lose. Only recently the last 3 years I was able to lose weight slowly and ironically it's also keeping in time with the tapering down of Xanax and Trazedone (an anti depressant). It's definitely something to think about, considering many psych meds increase ways to gain weight: thyroid abnormalities, all of that.

 

 

Anonymous
Peter (Pyrs)
2/ 8/09 10:07pm

My hunger sensations and appetite seem to me to be different on Paxil, at times almost irresistable. I never ever thought I'd be overweight like this. And I've basically given up on trying to lose it while on this antidepressant.

Note: I also take Wellbutrin (for SAD) and Ritalin (which replaced Adderall). I'd probably be heavier if it wasn't for the Ritalin (for ADHD).

 

2/ 9/09 1:56pm

Thank you for discussing this!  I was a sz 8-10 all of my life, even after kids -- at 52 my doctor convinced me to go on Paxil because of all the anxiety associated with working full-time/raising small children etc. etc.  I was having some terrible knee pain and serious sadness, plus peri-menopause, and she said the Paxil would  help with both.  Otherwise, she said I'd wind up with a major issue, like migraines or back pain, and that the Paxil would have no side effects. In a year I was up 40 pounds to a size 14!  No change in eating habits, though less exercise and lots of memory issues. 

 

When I talk to my new physician, she says, "You can try any of them, I'll prescribe them all.  No telling which will work."  It's SO discouraging that doctors seem to prescribe these drugs so quickly without any real thought about what they might do!!! 

My OB/GYN, head of a unversity Reproductive Services dept says there's no clear evidence that menopause causes weight gain -- I wouldn't mind some gain if it's part of the aging process, but I will NEVER believe that this excessive gain is due to anything but the Paxil -- amazing -- physicians dont' seem to understand that all this extra weight is not only more depressing, but unhealthy!

Now I've slowly gotten off the Paxil, and after looking at this site re: withdrawal symptoms, I realize the awful withdrawal effects from Paxil are not uncommon, even suicidal thoughts -- I'm miserable, but I won't go back -- now I have to lose all this weight on top of the issues

 

I can't wait for Part 2 of your series -- thanks so much.

 

2/ 9/09 1:56pm

Thank you for discussing this!  I was a sz 8-10 all of my life, even after kids -- at 52 my doctor convinced me to go on Paxil because of all the anxiety associated with working full-time/raising small children etc. etc.  I was having some terrible knee pain and serious sadness, plus peri-menopause, and she said the Paxil would  help with both.  Otherwise, she said I'd wind up with a major issue, like migraines or back pain, and that the Paxil would have no side effects. In a year I was up 40 pounds to a size 14!  No change in eating habits, though less exercise and lots of memory issues. 

 

When I talk to my new physician, she says, "You can try any of them, I'll prescribe them all.  No telling which will work."  It's SO discouraging that doctors seem to prescribe these drugs so quickly without any real thought about what they might do!!! 

My OB/GYN, head of a unversity Reproductive Services dept says there's no clear evidence that menopause causes weight gain -- I wouldn't mind some gain if it's part of the aging process, but I will NEVER believe that this excessive gain is due to anything but the Paxil -- amazing -- physicians dont' seem to understand that all this extra weight is not only more depressing, but unhealthy!

Now I've slowly gotten off the Paxil, and after looking at this site re: withdrawal symptoms, I realize the awful withdrawal effects from Paxil are not uncommon, even suicidal thoughts -- I'm miserable, but I won't go back -- now I have to lose all this weight on top of the issues

 

I can't wait for Part 2 of your series -- thanks so much.

 

2/10/09 8:03pm

Part two of my series can be found here!  Smile

3/ 5/11 1:52pm

In part 2, when talking about Effexor (SNRI), did you mean that it didn't have a tendancy toward weight GAIN...not loss?  ...and it is an antidepressant

3/ 5/11 5:55pm

Glad you found part two.

 

No...I don't believe there are any typos there in the quote.  I can see how it may be confusing though.  The main thing this author tries to explain is that SNRI's are less likely to cause you to gain weight than the SSRI's.  The author of the quote was pointing out that a weight loss drug, Merida, is an SNRI.  Please note that it was reported in the Fall of 2010 that Merida has been pulled from the shelves because of the extreme health risks associated with its use.  Other SNRI's are antidepressants such as Effexor which are not used or marketed for weight loss.  What the quoted author was concluding was that "...tiny changes in chemical structure can have big effects on the brain."

 

Other SNRI's which are also antidepressants include:  Effexor, Prestiq, and Cymbalta. 

 

As you can see though in the comments there are many people who have taken these SNRI's who have gained weight.  There are no hard and fast rules about this. 

 

If you have questions I would be glad to research an answer for you.  The main person you need to talk to, however, is your doctor.

 

 

 

 

 

 

Anonymous
Just Me
2/12/09 1:16pm

My experience with ALL SSRI's were NON-effective and caused me to gain up to 60lbs.  After 8 years of trying everything on the market, a new doctor put me on Cymbalta and Abilify.  I think when he added Abilify that's when I gained more weight again.  I'm also on Lithium.  Then he put me on Topomax--to help me lose weight--which WEIGHT GAIN is a side effect.  So finally, I had come to the end of my rope.  My concentration was abstract and drowsy, I was gaining weight, and I felt slow and tired, like everything was moving in slow motion.  At least my mom told me I LOOKED like I was moving in slow motion.  So I went to an On-Call Doctor-Mine was out of town.  He took me off the Topomax, lowered the dose of Abilify, and put me on a medication called Adderall.  They sometimes prescribe this med for kids with ADHD.  It is a stimulant, and it's great-- I feel like my old self--before the depression.  And I'm working and school is going great.  I'm attending classes, which was a big drawback before, I just didn't have the energy.  I know I should start exercising more and I would lose those last 10lbs., and be more fit.  I just haven't fit it into my schedule yet.

So that's my experience.  By the way Wellbutrin I tried twice--and both times it gave me vertigo so bad I was nauseous. Can not take Wellbutrin.  But Chantix has stopped me from smoking--worked like a charm.

Just Me

5/28/09 8:25pm

Chantix.   What is the wt. factor?   Also, how does Chantix impact other antidepressants?   Is it an antidepressant at all on its own?

5/28/09 8:25pm

Chantix.   What is the wt. factor?   Also, how does Chantix impact other antidepressants?   Is it an antidepressant at all on its own?

Anonymous
happy61
3/ 2/09 5:25pm

Finally here is,at least a part of, the reason I've gained so much weight in the last 10 years! I've been taking Zoloft that long, and I've probably gained 50 pounds! I'm 48 years old, so I realize that my age is part of it too. I had never had a weight problem up until this time. I've tried Weight Watchers and Curves, without very much sucess that lasts. I'm tempted to quit the Zoloft, although it has helped me greatly. I have clinical depression. My mother is Bipolar, but I am not. Depression runs in my family.

Anonymous
DCROY9633
5/ 2/09 7:58pm

<p>I had always been small -- a size 6.&nbsp; When I started taking Prozac, I lost my appetite completely and my weight plummeted to 93 lbs and a size 3.&nbsp; I had had anorexia and bulimia years before, so this was definitely scary.&nbsp; But then, my psychiatrist put me on Zyprexa for schizophrenia, and I quickly gained up to 186.&nbsp; Right now I have been on the Zyprexa for years and battle more weight gain every minute.&nbsp; It makes me ravenously hungry 24x7.&nbsp; My weight is down to 174, which isn't much of a victory.&nbsp; I am also taking Wellbutrin which supposedly aids in losing weight, but it can't stand against Zyprexa!&nbsp; I also took Tofranil back in the 60's and had no weight gain, and I took both Paxil and Effexor and had no weight gain. I guess it just varies a lot with the individual.</p>
<p>&nbsp;</p>
<p>Carolyn</p>

Anonymous
porkchop
6/30/09 9:19am

I have suffered from depression for a long time.  I have a family history of depression, where my mother was bi-polar.  I have tried many medicians, paxil, effexor, lexipro( cause me to have anxiety attacks when I never had one).  When I went on paxil to get rid of my anxiety attacks I gained 20-30 pounds.  I went on Wellbutrin but now that it is a generic I dont feel it is working.  I recently lost my job and 3 month ago I lost my mother.  I just want a medicine to make me "feel normal" without the weight gain.  Any sujesstions??????

Anonymous
Anonymous
7/21/09 11:54pm

Hi.  I was on Paxil for anxiety and depression for about 3 years.  At the time I was taking it I was under alot of stress so didn't realize at the time why I was gradually gaining weight.  As I look back if I had realized this I would have done something about it ie: ask for another medication. 

 

So, I can report to you that I gained about 35 lbs in that 3 year period but was totally unaware of it until I looked in the mirror one day and said "what the heck happened to my waistline?"  I have been unable to get this weight off of me since - and it has been 3 years.  I am 60 years old now.  I am very sad when I think of how much this drug "slowed down" my whole body.  I can even attribute a complete lack of sexual desire on Paxil - my marriage love life ended the year I went on Paxil. 

 

Although I was happy with the effects of Paxil otherwise I am very sad when I see the major changes it made in my weight and sexual desire.  I really felt very "empty" inside.

 

Thank you for this opportunity.

Anonymous
Jennifer
9/ 1/09 10:56am

I have been taking zoloft for app. 3 years and i have gained 30 - 40 pounds and I am miserable i am weening off of it right now. I have no energy and I feel like my appitiet has gone through the roof. I am going to stay off any kind of antidepressent for a while and see what happens. I think doctors are very quick just to put people on medicine without trying to find any other underlying issues. I also have an appoinment to have my thyroid checked next week and find it hard to believe that it was never checked before due to my symptoms, i am very tired, no energy, wieght gain, excessive facial hair growth all of which sounds to me like a thyroid or PCOS.

Anonymous
Anonymous
9/14/09 6:34pm

although i was involved in a nasty divorce and custody battle, i still came out haveing gained 40 lbs in 2 1/2 years on zoloft. Zoloft works for me with no side effects, (other than possible weight gain) i am now convinced after haveing to up my dose when things got tougher for the anxiety, that the weight is from the zoloft. i have tried diet and exercise, with no luck. I am  approaching my mid-fourties and am wondering it i am pre-menopausel also.

Witht that said, i am convinced zoloft is to blame and have scheduled an appointment with an endocrynologist to check all hormones and thyroid, etc.

Anonymous
SB
9/23/09 2:00pm

I started taking antidepressants just yesterday, and a weird side-effect it had on me was loss of wanting to eat or drink anything with flavor.

9/23/09 8:25pm

I've been on Zoloft for a bit now, and I've actually lost 17 pounds in the last month.  Zoloft seems to wipe my appetite out, and I'm actually starting to get a little nervous about it because I'm losing too muich too fast.  After the first 10 pounds, I thought, hey, this is nice, but now I'm a little worried.

10/21/09 4:19pm

Hey Sad Girl!

 

Was wondering if you could share about your Zoloft experience on my Member Medication Review?   I am really interesting in hearing how things are going for you now.

Anonymous
joyce
9/25/09 1:02am

After gaining 30  lbs after years of different ssri's I was prescibed paxil cr and lost weight. like 25 pounds!

 

Paxil is known for weight gain, but the paxil cr really helped.

I did watch the carbs though... but I didn't have such horrible cravings.

Anonymous
Hope?
11/23/09 12:36am

My doctor prescribed to me amitrytipline about one year ago to treat the severe pain associated with interstitial cystitis.  This is a very painful bladder condition that I have to live with the rest of my life.  Within 1 month, I had gained almost 10 pounds!!!!  I have also been taking on and off Prozac and Lexapro over the past 8 years to treat mild to moderate depression and mostly to help treat my eating disorder I have had for 17 years. While at my worst point with anorexia and bulimia, the prozac always seemed to balance my weight and my appetite to "normal" levels. It decreased cravings and binges and actually decreased my appetite all together. I do not feel I ever gained weight while on either of these meds.  Despite the eating disorder, my weight never went too much below a healthy range and I HAVE NEVER BEEN OVERWEIGHT! However, the amitryptiline is doing the exact opposite! I am currently 15 pounds over my "healthy" or "comfortable" weight and it is causing great anxiety!!! I have learned that the amitryptiline can increase sugar cravings and decrease metabolic rate, but without it, I get in significant pain that prevents me from being able to physically function day to day.  This is a lose-lose situation for me. My meds to treat IC and my eating disorder are causing me to gain extra weight, which is then triggering my old, unhealthy attempts at weightloss. Amitryptiline is a horrible drug for someone with an eating disorder, but is the only med to successfully treat the IC pain. Is there any solution??

Anonymous
Fatty Cakes
11/30/09 7:45pm

I have been on anti-depressants for about 10 years now.  I started out on Celexa, but I kept building up a tolerance to it so I constantly had to up my dosage.  Finally, I tried Zoloft, but it made me too tired, so I tried Welbutrin with it to counteract the fatigue.  That combination worked well for me, and for the first 5 years or so I was the same healthy weight (between 110 and 120 lbs) I'd always been.  Then, all of a sudden, the weight started to pack on and wouldn't stop.  I joined a gym, tried diet and exercise, even appetite surpressants and metabolism boosters, but to no avail.  The weight gain has only continued year after year.  I now weigh 160 and I look and feel horrible about myself.  My blood pressure has shot up and I sweat profusely after minimal exhertion.  I can't think of any other reason for the weight gain, so I've concluded that it has to be the medication.  True, I was on it for years with no complications, but I think the prolonged usage has really done terrible things to my metabolism.  I'd like to be able to ween myself off of it to see if it helps, but anytime I miss a dose, my entire body crashes from the withdrawl.  I fear for myself and others on the days I go without taking my meds. 

It's so frustrating and depressing and bothersome, and I don't know where to go or who to turn to for help, since all my doctors seem to think I'm gaining weight because I eat too much and exercise too little (which is not the case at all!).

Anonymous
Anonymous
12/25/09 1:41am

Zoloft & Depokote taken over a 2 year period made me have the biggest weight gain in my life.  I stopped taking Zoloft recently & take Wellbutrin. Plan to up exercise plan & my doctor seems to think this will help.

Anonymous
Shambri
1/25/10 12:25pm

I am 20 years old and went from a mere 122 lbs to 154 because of antidepressants. My doc misdiagnosed me with bipolar. And for the past two years its been one drug after another.  I am currently detoxing my body from all the medicines. And in the past week I have dropped 8 lbs. Antidepressants make you hungry. And amazingly, now that I have stopped, I eat like I used to eat!

2/22/10 11:35pm

I like part 1 of this article..... but have searched for part 2 and cannot find it.  Has it been posted yet and if so where can I find it?

Anonymous
jaytipton
2/24/10 2:45pm

What I really need to know is if the weight gain is of a controllable nature (i.e. Increased apetite) or uncontrollable like a lowered metabolism. I absolutely refuse to take a medication that will make me involuntarily gain weight, and I just want to know what the options are.

2/26/10 12:01pm

over the course of a year or so i have gained 35lbs with this drug.  i work out hard 4-5 times a week and do not eat anything after 8pm - ever!  yet i steadily gained weight.  the only possible cause if the effexor. i have now weened off it entirely.  i take 5-htp daily to take care of my panic attacks which is why i started it to begin  with.  now maybe the pounds will fly off as quickly as they came on!!

3/ 6/11 1:42pm

You take 5 htp daily?  People, don't use abreviations, wTH is htp?  Thanks

Anonymous
snl
3/19/10 9:18pm

I have definitely gained weight as my dosage of Zoloft has increased.  It is a strange weight gain, adding fat to areas where I've never previously struggled with it.  Also, constipation is a problem, so there's bloating--which doesn't help matters.  I've gone up one pant size.  I have already begun to decrease my dosage, and plan to be off the medication sometime in early summer.  In the meantime, I'm trying to eat better, not snack at night, and get outside to walk.  I've also noticed an increase in my desire for candy, which I've never had before.  I'm a cracker and cheese kind of gal.  In general, I think it is messing with my body more than I'm comfortable with.  It served it's purpose for awhile, but I need to be done now.  The weight gain and constipation are a problem!

Anonymous
Anxi
12/17/10 5:15pm

I was on citrolopram generic for celexa.  As soon as I started taking it I was starving all the time.  I constantly felt hunger pains and so I ate and ate and gained 25 pounds in 6 months.  As soon as I stopped taking it I didn't feel hungry any more.  I then tried Well butrin but it made my anxiety get worse.  I am now going to try prozac.  I am hoping to find something that won't make me hungry but ease my anxiety.

2/ 5/11 11:30am

Stay away from Seroquel, if you can help it, and ask your doctor to prescribe an alternative, please!  I've taken it for my sleep disorder/insomnia and it causes significant weight gain!  Even when I'm carefully monitoring my caloric intake and exercising exorbitantly, I still found that I was carrying at least two to four pounds of extra weight.  And if you're trying to lose weight, it exacerbates the process to the infuriating point where the weight only comes off in dribs and drabs.  When I took myself off of Seroquel, my weight dropped DRAMATICALLY within one to two weeks! Find an alternative if you can.  Seroquel and its side effects have been exposed recently and getting a bad rap in the medical community anyway. 

3/ 4/11 2:58pm

This author said she will be talking about antidepressants that don't cause weight gain...and even that will help quit smoking!  Where is it?  She never told us which antidepressant that was!!  So frustrating...

3/ 4/11 8:57pm

Hi there

 

I am sorry I did not say where to find Part Two.

 

Here is the link to Part Two of this article.

 

Hope this helps!

 

Thanks for reading my posts.

 

 

3/ 4/11 10:26pm

I think if you'll look at comment# 21 above, you will see that the author did indeed link to Part Two a long time ago. It just takes some reading...

3/19/11 1:35pm

I hate when anyone tries to blame this weight gain on "maybe you're happier so you're eating a little more." Many years ago I tried Zoloft and went from 109 pounds to 123 in less than a month.  I am a gym rat and no one can eat that many cheeseburgers.  Fortunately I have an inquiring mind so I cornered a pharmacist at a dinner party one night and he explained that the weight gain was connected to the way in which some of these antidepressant alter enzymes ( or some such mechanism) in the liver and that is the thing that leads to weight gain.  Now this does not explain why two people can take the same drug and only one gains weight.  But it oes let you know that if you ar a weight gainer on these drugs it's not necessarily from what you're putting in your moth besides the drug.  I'm still trying to lose the extra ten pound I put on from Prozac a year ago.

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By Merely Me— Last Modified: 07/03/11, First Published: 02/02/09