I suffer from depression. In fact, i am on Social Security Disability because of it. i was taking Zolof to help with my depression. It worked very well. I started taking Chantix to quit smoking.  I did so very easily while on Chantix.  I continued taking the Chantix for 2 months or more after quitting, as this is recommened by Chantix Manufacturers.  Because I was becoming more depressed (a side effect of Chantix) my Doctor raised my my dosage of Zolof to 100 mgs twice daily. I ended up in the hopital with a Seratonin reaction.  The entire left side of my face lost all muscle support and basicly collasped. The droops came and went, about 15 to 20 minutes apart. I stopped taking Chantix and healed in about 24 hours.  Beware. Chantix works great, but stay in complete communication with you Doctor at all times.