Several years ago, Itook Effexor for 6 months, and tolerated fairly well, except for severe constipation and insomnia. After being taken off HRT abruptly in '02, Effexor had an agitating effect. PCP recently prescribed Cymbalta 40, but by evening I was extremeliy agitated. My PCP has now given me Pristiq 50. If I previously had been able to tolerate Effexor, would I now be able to tolerate Pristiq? I have a concern about eye pressure, and Pristiq has warnings about eye problems. Although I do not have glaucoma, I have elevated IOP, in the safe range, but my eye doctor has prescribed Xalatan. I need to take some type of antidepressant for insomnia/anxiety, and need to know which would be most effective and safest for my eye pressure issue. Would much appreciated advice, as I am much in need of an effective medication.




